Sökning: "gene duplication"
Visar resultat 21 - 25 av 112 avhandlingar innehållade orden gene duplication.
21. Gene dose imbalances in children with mental retardation
Sammanfattning : Submicroscopic chromosome aberrations can cause mental retardation (MR), congenital malformations and miscarriage. It is difficult to estimate the contribution of cytogenetic abnormalities to MR because of relatively low detection sensitivity of conventional cytogenetic methods used in the diagnostic setting. LÄS MER
22. Genome instability, gene expression and prognosis in breast cancer
Sammanfattning : Aneuploid cancers are regarded as being more malignant than tumors of other ploidy categories, and they are characterized by increased genomic instability. Our investigations resulted in the characterization of an aneuploid subtype of breast carcinoma that proved to be genomically stable. LÄS MER
23. Exploring the role of gene duplications in plant-insect interactions
Sammanfattning : As evolutionary biologists, we are often curious about the genomic origins of our favorite adaptations. Although some innovations certainly arose de novo, many more originated through the process of whole-gene or within-gene duplication. LÄS MER
24. Probabilistic Models for Species Tree Inference and Orthology Analysis
Sammanfattning : A phylogenetic tree is used to model gene evolution and species evolution using molecular sequence data. For artifactual and biological reasons, a gene tree may differ from a species tree, a phenomenon known as gene tree-species tree incongruence. Assuming the presence of one or more evolutionary events, e.g. LÄS MER
25. Genomic and phenotypic consequences of allopolyploidization in Capsella
Sammanfattning : Allopolyploidization, the combination of whole-genome duplication (WGD) and interspecific hybridization, is a frequent and influential event in plant evolution. Allopolyploidization potentially affects both adaptation and diversification, yet the understanding of the consequences of allopolyploidy has been obscured by several issues. LÄS MER