Sökning: "false positive results"

Visar resultat 16 - 20 av 106 avhandlingar innehållade orden false positive results.

  1. 16. Cytomegalovirus and herpes simplex virus infections in the fetus and newborn infant, with regard to neurodevelopmental disabilities

    Författare :Mona-Lisa Engman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The congenital cytomegalovirus infection (CMV) is the most common congenital infection causing childhood morbidity. The majority (85%) of infected infants have no signs of infection in the newborn period, and when sequelae such as a hearing deficit or neurological impairment manifest themselves, the possibility of a CMV infection is easily overlooked. LÄS MER

  2. 17. Studies on the reliability of biomarkers for alcohol use and abuse

    Författare :Naama Modén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alcohol is consumed by the vast majority of the population, but prolonged excessive drinking is associated with various negative health and social consequences. It is therefore important to identify individuals with at-risk alcohol consumption, before it turns into abuse or dependence. LÄS MER

  3. 18. Mechanisms of resistance to ciprofloxacin in Neisseria gonorrhoeae

    Författare :Emma Lindbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neisseria gonorrhoeae; ciprofloxacin; DNA-gyrase; topoisomerase IV; major outer membrane protein;

    Sammanfattning : A few years ago, most strains of Neisseria gonorrhoeae were susceptible to ciprofloxacin, but after introduction as a first line therapy, resistant strains emerged. Ciprofloxacin inhibit two enzymes necessary for DNA replication. LÄS MER

  4. 19. Analysis of drugs and proteins in biological matrices, using different types of sample preparations and mass spectrometry

    Författare :Aljona Saleh; Ingrid Granelli; Jonas Bergquist; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bioanalysis; drugs; proteins; liquid chromatography; two-dimensional liquid chromatography; mass spectrometry; Analytical Chemistry; analytisk kemi;

    Sammanfattning : This thesis describes bioanalysis of small and large molecules in biological matrices and includes screening of illegal drugs in urine with high resolution mass spectrometer, bioanalysis of MTH1 inhibitors in mice plasma and quantification of proteins in plasma and cell lysates.Screening of illegal drugs was based on high resolving power mass spectrometer (QTOF) and the results were compared to immunoassays. LÄS MER

  5. 20. Incidence and interval breast cancers in retrospective assessment

    Författare :Kerstin Moberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Breast neoplasm; mammography screening; computer aided detection; interval breast cancer; incidence breast cancer;

    Sammanfattning : The aims of this thesis were to investigate how different review methods used for radiological classification of breast cancers would affect the proportion judged to be false negative, to investigate how computer aided detection (CAD) would affect screening sensitivity, to study the balance between false positive and false negative results and to investigate patient outcome in relation to review result. In a mass screening programme in Stockholm, commencing in 1989 and performed at five independent screening units, interval cancers (presenting in the time interval between two consecutive screening examinations) from two of the units, 103 women, and incidence cancers (diagnosed at subsequent screening examination) from one of the units, 117 women, diagnosed up until July 1993 were identified. LÄS MER