Sökning: "erik lundgren"

Visar resultat 11 - 15 av 21 avhandlingar innehållade orden erik lundgren.

  1. 11. Prefibrillar oligomeric Transthyretin mutants - amyloid conformation, toxicity and association with Serum amyloid P component

    Författare :Karin Andersson; Erik Lundgren; Anne Clark; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : Amyloidoses represent a heterogeneous group of diseases characterized by abnormal protein metabolism leading to extracellular deposition of fibrillar, proteinaceous amyloid in various tissues and organs of the body. To date more than 20 different proteins have been linked to diseases with amyloid depositions, of which Alzheimer’s disease and the prion-associated diseases are the most well known. LÄS MER

  3. 12. Regulation of apoptosis during treatment and resistance development in tumour cells

    Författare :Jeanette Blomberg; Erik Lundgren; John Eriksson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumörbiologi; Tumour biology; Tumörbiologi;

    Sammanfattning : Induction of apoptosis is the most studied cell death process and it is a tightly regulated physiological event that enables elimination of damaged and unwanted cells. Apoptosis can be induced via activation of either the intrinsic or the extrinsic signalling pathway. LÄS MER

  4. 13. Aspects of interferon alpha signalling in hematopoetic cells

    Författare :Lennart Carlsson; erik lundgren; Ulrich Kalinke; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; interferon; human; B-lymphocyte; survival; proliferation; myeloma; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The type I interferons (IFN) are a family of cytokines with pleiothropic activities that include inhibition of viral replication, cell proliferation and activation of the immune system. These properties give the IFNs important physiological and pathological roles in infection and cancer and have led to their therapeutic use for many clinical conditions. LÄS MER

  5. 14. Opportunities to broaden biomass feedstocks in thermochemical conversion technologies

    Författare :Lara Carvalho; Joakim Lundgren; Elisabeth Wetterlund; Erik Furusjö; Andrea Ramírez Ramírez; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Non-woody biomass; Combustion; Gasification; Biofuels; Techno-economic analysis; Energiteknik; Energy Engineering;

    Sammanfattning : Global environmental concerns are motivating a growing interest in broadening the biomass feedstock base in several energy sectors, including (i) the domestic heating sector, presently dominated by stem wood combustion, and (ii) biofuel production, presently dominated by edible crops. The objective of this thesis is to investigate new opportunities to broaden the biomass feedstock in thermochemical conversion technologies. LÄS MER

  7. 15. Functional and molecular aspects of interferon action in human natural killer cells and other leucocytes

    Författare :Åke Gustafsson; Erik Lundgren; Umeå universitet; []
    Nyckelord :natural killer cell; large granular lymphocyte; interferon; interferon production; interferon-induced; protein synthesis; two-dimensional electrophoresis;

    Sammanfattning : Interferons comprise a class of structurally related proteins which exert several regulatory effects in responsive cells. These effects include the establishment of an antiviral state, the inhibition of cellular proliferation and the alteration of different immune reactions. LÄS MER