Sökning: "natural killer cell"

Visar resultat 1 - 5 av 197 avhandlingar innehållade orden natural killer cell.

  1. 1. Mechanisms regulating Natural Killer Cell Cytotoxicity

    Författare :Hanna van Ooijen; Björn Önfelt; Karl-Johan Malmberg; Karolin Guldevall; Morgan Huse; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Natural Killer cell; Live-cell microscopy; Single cell; 3D; Microwell;

    Sammanfattning : Over the last 50 years, cancer survival rates have steadily improved thanks to earlier detection and novel treatment regimens. For example, drugs that act on the immune system, so-called immunotherapy, have drastically increased the prospect of survival for patients suffering from some of the most aggressive cancer types including advanced malignant melanoma. LÄS MER

  3. 2. Natural killer cells : studies on genetic, endogenous and exogenous factors controlling the expression of natural killer cell activity

    Författare :Anders Örn; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  4. 3. Ultrasonic Fluid and Cell Manipulation

    Författare :Mathias Ohlin; Martin Viklund; Hans Hertz; Peter Glynne-Jones; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 3D cell culture; Acoustic streaming; Acoustofluidics; Cell manipulation; High-resolution imaging; Multi-well; Microplate; Natural killer cell; Piezo; Radiation force; Solid tumor; Solubilization; Spheroid; Standing wave; Temperature control; Transducer; Trapping; Ultrasonic; Fysik; Physics; Biological Physics; Biologisk fysik;

    Sammanfattning : During the last decade, ultrasonic manipulation has matured into an important tool with a wide range of applications, from fundamental cell biological research to clinical and industrial implementations. The contactless nature of ultrasound makes it possible to manipulate living cells in a gentle way, e.g. LÄS MER

  5. 4. Matrix metalloproteinases in natural killer cells. Expression of MMPs, IL-2 activation and killer cell interactions with Matrigel® and model tumours

    Författare :Per Albertsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease; matrix metalloproteinase; killer cell; IL-2; Matrigel; B16 melanoma; tumour infiltration; invasion assay; zymography; Western blot; RT-PCR; light microscopy; fluorescence; electron microscopy;

    Sammanfattning : Introduction: IL-2 activated natural killer (A-NK) cells can recognize malignant cells and exert tumouricidal activities by multiple mechanisms that require close contact with the target cells. Upon adoptive transfer, some A-NK cells accumulate in tumours by migrating from the vascular bed to a position inside the malignant tissue, forming close contacts with target cells. LÄS MER

  7. 5. Imaging-based methods for NK cell studies at the single-cell level

    Författare :Quentin Verron; Björn Önfelt; Niklas Sandström; Michael Dustin; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; NK cells; microscopy; single-cell; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : The immune system provides defense against infectious agents such as viruses, bacteria and parasites. Besides eliminating extracellular agents, the immune system also constantly monitors our own cells for signs of transformation, including tumor development and virus infection. LÄS MER