Sökning: "interferon-induced"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet interferon-induced.

  1. 1. Functional and molecular aspects of interferon action in human natural killer cells and other leucocytes

    Författare :Åke Gustafsson; Erik Lundgren; Umeå universitet; []
    Nyckelord :natural killer cell; large granular lymphocyte; interferon; interferon production; interferon-induced; protein synthesis; two-dimensional electrophoresis;

    Sammanfattning : Interferons comprise a class of structurally related proteins which exert several regulatory effects in responsive cells. These effects include the establishment of an antiviral state, the inhibition of cellular proliferation and the alteration of different immune reactions. LÄS MER

  3. 2. Crimean-Congo hemorrhagic fever virus : interferon-induced antiviral mechanisms and immune evasion strategies

    Författare :Ida Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Bunyaviridae family is the largest virus family consisting of more than 350 viruses. Despite the increasing knowledge regarding the biology of members of this family, little is known about Crimean-Congo hemorrhagic fever virus (CCHFV), a virus classified within the Nairovirus genus and the causative agent of a severe hemorrhagic fever in humans with high mortality. LÄS MER

  4. 3. Regulation of apoptosis during treatment and resistance development in tumour cells

    Författare :Jeanette Blomberg; Erik Lundgren; John Eriksson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tumörbiologi; Tumour biology; Tumörbiologi;

    Sammanfattning : Induction of apoptosis is the most studied cell death process and it is a tightly regulated physiological event that enables elimination of damaged and unwanted cells. Apoptosis can be induced via activation of either the intrinsic or the extrinsic signalling pathway. LÄS MER

  5. 4. Neuroendocrine tumors of the digestive system : Modulation of apoptosis and factors associated with growth regulation during biotherapies

    Författare :S. A. Hassan Imam; Uppsala universitet; []
    Nyckelord :Medical sciences; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

    Sammanfattning : Neuroendocrine tumors of the gut have the potential to create life-threatening syndromes which become difficult to treat. Tumor mass reduction, by medical therapy, is one of the choices of treatments. LÄS MER

  7. 5. Epigenetic and Gene Expression Signatures in Systemic Inflammatory Autoimmune Diseases

    Författare :Juliana Imgenberg-Kreuz; Gunnel Nordmark; Ann-Christine Syvänen; Johanna K Sandling; Amr Sawalha; Uppsala universitet; []
    Nyckelord :Autoimmunity; DNA methylation; Primary Sjögren’s syndrome; Systemic lupus erythematosus; Gene expression; Type I interferon system; Epigenetics; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Autoimmune diseases are clinical manifestations of a loss-of-tolerance of the immune system against the body’s own substances and healthy tissues. Primary Sjögren’s syndrome (pSS) and systemic lupus erythematosus (SLE) are two chronic inflammatory autoimmune diseases characterized by autoantibody production and an activated type I interferon system. LÄS MER