Sökning: "drosophila differentiation"

Visar resultat 21 - 25 av 36 avhandlingar innehållade orden drosophila differentiation.

  1. 21. A screen for mutations affecting PNS development in Drosophila identifies the trim gene, dappled

    Författare :Fergal O'Farrell; Per Kylsten; Jan-Åke Gustafsson; Stefan Thor; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The peripheral nervous system of Drosophila melanogaster contains a variety of sense organs, ranging from the relatively simple four celled bristle organ to the more complex compound eye. The development of each organ type is well described, providing a useful backdrop for functional studies of genes acting in one or more of the many processes involved in organogenesis. LÄS MER

  3. 22. On the role of notch, numb and numblike in development and cancer

    Författare :Lining Liu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development of mutlicellualr organisms relies on a highly conserved signaling network, of which one of the key components is the Notch signaling pathway. The core Notch signaling pathway consists of receptors, ligands and an intracellular mediator. LÄS MER

  4. 23. The rhomboid family of intramembrane proteases, conserved regulators of cell communication

    Författare :Marco Gallio; Per Kylsten; Pernille Rørth; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell communication; proteolysis; EGF receptor; development; genetics;

    Sammanfattning : The development of multicellular organisms relies heavily on cell communication. Cells send and receive complex sets of signals, harmonising their growth and differentiation with that of other, often distant, cell populations. In animals, the Epidermal Growth Factor Receptor (EGFR) is an important mediator of cell communication. LÄS MER

  5. 24. Adult neural stem cells in neuroinflammation

    Författare :Ruxandra Covacu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Neural stem cells; inflammation; EAE; NO; neurogenesis; HMGB1; TLR; TNFalpha;

    Sammanfattning : Adult neural stem cells (NSC) can be isolated from the subventricular zone (SVZ) of the lateral ventricles, the subgranular zone (SGZ) of the hippocampus and the central canal of the spinal cord. These cells are thought to have regenerative potential and pose important therapeutic possibilities in neuroinflammatory conditions such as Multiple Sclerosis (MS). LÄS MER

  7. 25. The Role of HoxB4 in Hematopoiesis

    Författare :Ann Brun; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; Haematology; extracellular fluids; adenovirus; gene transfer; knock out; HOXB4; HOXB3; homeobox genes; hematopoietic stem cells; Transcription factors; hematopoiesis;

    Sammanfattning : HOXB4 is one of 39 members of the homeobox (HOX) family, a family of transcription factors involved in embryonic development. Several HOX transcription factors, including HOXB4, are highly expressed in hematopoietic stem cells (HSCs) but are downregulated upon differentiation towards more mature progeny cells. LÄS MER