Sökning: "damage associated molecular patterns"

Visar resultat 16 - 20 av 23 avhandlingar innehållade orden damage associated molecular patterns.

  1. 16. On dysregulated inflammation and airway host defense

    Författare :Ravi K. V. Bhongir; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aiway inflammation; Chronic obstructive pulmonary disease COPD ; Cystic Fibrosis; Pseudomonas aeruginosa; DNase I;

    Sammanfattning : Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) are characterized by dysregulated inflammation of the airways. The increased influx of immune cells and the accumulation of cytokines lead to cell death, tissue destruction and impaired pulmonary function. LÄS MER

  3. 17. Genotoxic stress : novel biomarkers and detection methods : uncovering RNAs role in epigenetics of carcinogenesis

    Författare :Edyta Zofia Bajak; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cancer is a complex disease that is caused by the interplay of multiple genes and diverse environmental factors. As such, there has been continual debate as to which component of this complicated process towards development of neoplasia plays the most important role. LÄS MER

  4. 18. In silico analysis of pathways targeted by EBV infection and malignant transformation

    Författare :Ramakrishna Rao Sompallae; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Bioinformatics; systems biology; gene expression analysis; Epstein-Barr virus; Burkitt s lymphoma;

    Sammanfattning : Epstein-Barr virus (EBV) is a ubiquitous γ-herpes virus with dual cell tropism for human B-lymphocytes and epithelial cells. EBV infection is linked to several malignancies such as Burkitt s lymphoma (BL) and nasopharyngeal carcinoma (NPC). LÄS MER

  5. 19. Epigenetic and bioelectronic tools to study neural stem cells in health and disease

    Författare :Christina Neofytou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Brain development is a highly controlled, complex, and dynamic process. The mechanisms of its control need to accommodate the constantly changing contexts which, overtime, support the emergence of new neural structures and functions. LÄS MER

  7. 20. Host-pathogen interactions in invasive Staphylococcus aureus infections

    Författare :Srikanth Mairpady Shambat; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Staphylococcus aureus is a versatile human pathogen causing a wide range of diseases from uncomplicated skin and soft tissue infections to life-threatening invasive diseases like endocarditis, bacteremia, necrotizing pneumonia, and fasciitis. The pathogen has become increasingly resistant to -lactam antibiotics, and of special concern is the rise in community- acquired (CA)-MRSA strains, as specific CA-MRSA clones have been associated with highly aggressive infections. LÄS MER