Sökning: "circulating tumor cell"

Visar resultat 16 - 20 av 61 avhandlingar innehållade orden circulating tumor cell.

  1. 16. Microfluidic based isolation of circulating tumor cells from whole blood for cancer diagnostics

    Författare :Harisha Ramachandraiah; Aman Russom; Klas Hjort; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biotechnology; Bioteknologi;

    Sammanfattning : Detection of circulating tumor cells (CTC) in peripheral blood is indicative of early recognition of tumor progression and such an important biomarker for early diagnosis, staging, monitoring and prognosis of cancer. However, CTC are found in very low concentrations and reliable isolation of these rare cells is challenging. LÄS MER

  3. 17. Translational and clinical aspects of pancreatic cancer

    Författare :Caroline Vilhav; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic cancer; circulating tumor cells; extracellular vesicles; immunotherapy; PDX model; pancreaticoduodenectomy; postoperative complications; postpancreatectomy hemorrhage;

    Sammanfattning : Pancreatic cancer is a disease with dismal prognosis due to late detection and ineffective treatments. The majority of the patients already have disseminated disease at the time of diagnosis. The only potential curative treatment, surgery, is extensive with high morbidity and non-ignorable mortality. LÄS MER

  4. 18. The application of microfluidic devices and multifunctional fibers in cancer diagnostics

    Författare :Tharagan Kumar; Aman Russom; Fredrik Laurell; Gustaf Mårtensson; Johan Kreuger; KTH; []
    Nyckelord :Circulating tumor cells; microfluidics; point of care; inertial microfluidics; elasto inertial microfluidics; nano-cellulose; layer-by-layer; optical fiber; microflow cytometer.; Bioteknologi; Biotechnology;

    Sammanfattning : Efficient separation and detection of rare cells in a mixed population is important in many biomedical applications. For instance, isolating and detecting circulating tumor cells (CTCs) from whole blood samples could allow for early cancer diagnosis and prognosis during treatment. LÄS MER

  5. 19. Receptor tyrosine kinases and circulating tumor cells as new prognostic biomarkers in breast cancer with special focus on TNBC

    Författare :Sara Jansson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bröstcancer;

    Sammanfattning : About 8000 Swedish women are diagnosed with breast cancer each year, and around 1500 die from the disease. Triple-negative breast cancer (TNBC) constitutes 7-14% of all breast cancer and is characterized by an aggressive phenotype with poor prognosis and no targeted therapy available. LÄS MER

  7. 20. Novel imaging technology and tools for biomarker detection in cancer

    Författare :Zahra El-Schich; Malmö högskola; []
    Nyckelord :Biomarkers; Kronisk lymfatisk leukemi; Early detection of cancer; Diagnosis; Leukemia; Lymphocytic; Chronic; B-Cell; Apoptosis; Digital holografi;

    Sammanfattning : Cancer is a leading cause of death worldwide. Normally the balance betweencell growth and cell death is strongly controlled. Chronic lymphocytic leukemiais an indolent disease that has a highly variable clinical course and is the mostcommon hematological malignancy amongst adults in the Western countries. LÄS MER