Sökning: "cholesterol"

Visar resultat 21 - 25 av 623 avhandlingar innehållade ordet cholesterol.

  1. 21. Structure and function of the HDL receptor SR-BI : scavenger receptor class B type I

    Författare :Magnus S.C. Johnson; Göteborgs universitet; []
    Nyckelord :SR-BI; HDL; Cholesterol; Scavenger receptor; Apoptosis; Ovary; Gallbladder; Peroxisome;

    Sammanfattning : Low plasma levels of high-density lipoprotein (HDL) and high levels of low-density lipoprotein (LDL) are well-recognized risk factors for cardiovascular disease. The uptake and degradation of LDL cholesterol have been characterized in detail at the molecular level. Less is known about the metabolism and cellular uptake of HDL cholesterol. LÄS MER

  3. 22. Self-Assembly in Lipid-Protein Systems : Lung Surfactant, Stratum Corneum and Model Membranes

    Författare :Jenny Andersson; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipid self-assembly; lung surfactant; stratum corneum; dehydrin; cholesterol; osmolytes; urea; TMAO; ssNMR; cSAXS;

    Sammanfattning : This thesis explores lipid self-assembly and aims to give a broad picture of self-assembly structures in simple and complex lipid-protein systems. The systems studied are lung surfactant, stratum corneum and simple model membranes. The lung surfactant mixture lines the alveolus in our lungs and stabilises the air- tissue interface. LÄS MER

  4. 23. Risk factors for fractures - a link between metabolic bone disease and cardiovascular disease

    Författare :Penelope Trimpou; Göteborgs universitet; []
    Nyckelord :Risk factors; General population; Physical activity; Sex hormones; Cholesterol; Stroke; Fracture;

    Sammanfattning : Introduction: Fractures and cardiovascular disease (CVD) are a burden to society, as they result in high morbidity and mortality in both men and women. Aim: The aim was to study prospectively modifiable risk factors for fractures in the general population and to possibly identify a link between metabolic bone disease and CVD. LÄS MER

  5. 24. Methods for elucidating membrane protein structure and function

    Författare :Carolina Trkulja; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; patch clamp; antibodies; mass spectrometry; ion channels; proteomics; fluorescence; TRPV1; cholesterol.; limited proteolysis; Membrane proteins;

    Sammanfattning : Elucidation of the structure-function relationship of membrane proteins increases our understanding of many biological processes, both physiological and pathological. However, membrane proteins have been notoriously difficult to study, having part of their structure embedded into the lipid cell membrane. LÄS MER

  7. 25. Omics Techniques Applied to Diabetes Research - Focus on HSL-Null Mice and Clonal β-Cells

    Författare :Celine Fernandez; Molekylär endokrinologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolomics; transcriptomics; treadmill; liver; HSL; cholesterol; proteomics;

    Sammanfattning : Diabetes mellitus is a disease characterized by increased blood glucose levels. For overt type 2 diabetes to develop, both insulin action and insulin secretion must be perturbed. LÄS MER