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Visar resultat 1 - 5 av 28 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Miniaturised Microwell-based Cell Assays

    Författare :Emilie Weibull; Helene Andersson Svahn; Albert van den Berg; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microwell; miniaturisation; high-resolution imaging; high-throughput; cell culture; single-cell; clone; heterogeneity; antibiotic susceptibility testing; concentration gradient; interfacing; microchannels; cell retrieval;

    Sammanfattning : Cell heterogeneity in genetically identical cell populations is becoming a well-known and important phenomenon in cell biology. Current methods commonly utilise population-based analysis founded on averaged result. Hence there is a need for high-throughput cell assays on the single-cell level. LÄS MER

  3. 2. Imaging-based methods for NK cell studies at the single-cell level

    Författare :Quentin Verron; Björn Önfelt; Niklas Sandström; Michael Dustin; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; NK cells; microscopy; single-cell; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : The immune system provides defense against infectious agents such as viruses, bacteria and parasites. Besides eliminating extracellular agents, the immune system also constantly monitors our own cells for signs of transformation, including tumor development and virus infection. LÄS MER

  4. 3. Challenges in Islet Transplantation and Strategies to Improve Beta-Cell Function

    Författare :Hanna Liljebäck; Per-Ola Carlsson; James Shaw; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet transplantation; Type 1 diabetes; Mesenchymal stem cells; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : The incidence of type 1 diabetes is increasing worldwide and therapies of islet transplantation and potential cell-based therapies are rapidly evolving. Choosing the optimal site for such therapies is crucial for safety and for obtaining the best possible outcome. LÄS MER

  5. 4. Molecular Analysis of Normal Human Skin and Basal Cell Carcinoma Using Microdissection Based Methods

    Författare :Anna Asplund; Fredrik Pontén; Uffe Birk Jenssen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; skin; basal cell carcinoma; microdissection; X-chromosome inactivation; Patologi; Pathology; Patologi;

    Sammanfattning : The aim of this thesis was to gain further insight into the biology of normal human skin and basal cell carcinoma (BCC). Morphology in combination with microdissection was used as primary tool for sampling. LÄS MER

  7. 5. Nanowires in Cell Biology

    Författare :Henrik Persson; Fasta tillståndets fysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phase holographic microscopy; Nanowires; living cells; cell injection; Fysicumarkivet A:2014:Persson;

    Sammanfattning : This thesis explores the interactions between cells and nanowires, to increase our understanding of how cells are affected and how they can be manipulated by these one-dimensional, semiconductor crystals (lengths 1-10 µm, diameters .... LÄS MER