Sökning: "microdissection"
Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet microdissection.
1. Molecular Analysis of Normal Human Skin and Basal Cell Carcinoma Using Microdissection Based Methods
Sammanfattning : The aim of this thesis was to gain further insight into the biology of normal human skin and basal cell carcinoma (BCC). Morphology in combination with microdissection was used as primary tool for sampling. LÄS MER
2. p53 Alterations in Human Skin : A Molecular Study Based on Morphology
Sammanfattning : Mutation of the p53 gene appears to be an early event in skin cancer development. The present study is based on morphology and represents a cellular and genetic investigation of p53 alterations in normal human skin and basal cell cancer. LÄS MER
3. Transcriptome analysis on in vivo derived laser microbeam microdissected cells. Analysis of smooth muscle transcriptomes
Sammanfattning : Smooth muscle cells (SMCs) are found in the respiratory, urogenital, circulatory and digestive systems. They provide contractility and structural support for those organs and perform multiple physiological important functions, such as modulation of blood pressure, regulation of airway resistance, and control of gastrointestinal and genitourinary motility. LÄS MER
4. Small Intestinal Neuroendocrine Tumor Analyses : Somatostatin Analog Effects and MicroRNA Profiling
Sammanfattning : Small intestinal neuroendocrine tumors (SI-NETs) originate from serotonin-producing enterochromaffin (EC) cells in the intestinal mucosa. Somatostatin analogs (SSAs) are mainly used to control hormonal secretion and tumor growth. However, the molecular mechanisms leading to the control of SI-NETs are unknown. LÄS MER
5. Experimental Diagnostics and Therapeutics of Invasive Urinary Bladder Cancer
Sammanfattning : The two purposes of this thesis were to evaluate new diagnostic techniques of lymphnode staging in invasive bladder cancer and to evaluate the results of neoadjuvant chemotherapy in invasive bladder cancer.Sentinel node detection was performed in 13 patients in preparation for radical cystectomy. LÄS MER