Sökning: "caspase"

Visar resultat 41 - 45 av 267 avhandlingar innehållade ordet caspase.

  1. 41. Studies on microglia in tumor biology and neurobiology

    Författare :Xianli Shen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Microglia are innate immune cells that reside in the central nervous system (CNS). Their activities are critical for ensuring the correct microenvironment for brain development and for maintaining homeostasis in the brain after birth. LÄS MER

  3. 42. Regulation of neutrophil apoptosis

    Författare :Maria Alvarado-Kristensson; Malmö Molekylär patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; General pathology; pathological anatomy; Patologi allmän ; patologisk anatomi; PP2A; p38 MAPK; caspases; signal transduction; inflammation; Apoptosis; human neutrophils;

    Sammanfattning : The human neutrophil is the most abundant granulocyte and the major type of cell involved in an acute inflammatory response. Neutrophils are armed with various systems of enzymes, that can find and kill pathogens, but unfortunately, these "weapons" cannot distinguish between the host tissues and the "invaders. LÄS MER

  4. 43. Thiol redox state in apoptosis : physiological and toxicant modulation

    Författare :Stefan Nobel; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Apoptosis is a physiological type of cell death used to regulate the number of cells during development and in adult organs. However, apoptosis can also be inappropriately activated or inhibited under pathological conditions. One of the critical mechanisms of apoptosis is the activity of cysteine proteases belonging to the caspase family. LÄS MER

  5. 44. Regulation of apoptotic processes in neurodegeneration and cancer : In vitro studies on human neuroblastoma cells

    Författare :Tom Gatsinzi; Kerstin Iverfeldt; Thomas J. Sayers; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Apoptosis is a highly controlled process of cell death, which is vital for maintenance of all multicellular organisms. Aberrant regulation of apoptosis can give rise to pathological conditions such as neurodegenerative diseases and cancer. LÄS MER

  7. 45. The role of the mitochondrion in organotin-induced T-cell apoptosis

    Författare :Hélène Stridh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Apoptosis plays a central role in the development and the function of the immune system. The cell death program can, however, be inappropriately activated or suppressed under pathological conditions. Several toxins have been shown to interfere with intra-thymic processes, thereby contributing to autoimmune disorders. LÄS MER