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Visar resultat 1 - 5 av 151 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Filamin A in Cardiovascular Remodeling

    Författare :Sashidar Bandaru; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Filamin A; Cardiovascular remodelling;

    Sammanfattning : Filamin A (FLNA) is a large actin-binding cytoskeletal protein that stabilizes actin networks and integrates them with cell membranes. FLNA is therefore important for cell motility and organ development. LÄS MER

  2. 2. Novel functions of cardiovascular P2 receptors

    Författare :Anna-Karin Wihlborg; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiovascular system; Kardiovaskulära systemet; mRNA; EDHF; UTP; UDP; ADP; ATP; P2 receptor; contraction; dilatation; endothelial cells; Heart; VSMC;

    Sammanfattning : The aim of the thesis was to examine the expression and function of the extracellular nucleotide P2 receptors in the cardiovascular system. In the cardiovascular system nucleotides are released during shear stress, hypoxia, ischemia, from endothelial cells, smooth muscle cells, aggregating platelets, inflammatory cells and erythrocytes. LÄS MER

  3. 3. Cardiovascular responses to hypovolemic circulatory stress in women : With special reference to venous compliance and capacitance

    Författare :Marcus Lindenberger; Toste Länne; Peter Friberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiology; Kardiologi;

    Sammanfattning : Acute haemorrhage is a leading cause of death in trauma. Young women (YW) seem more susceptible to hypovolemic circulatory stress than young men (YM), but the underlying mechanisms are not clear. LÄS MER

  4. 4. Regulatory Immune Responses and Repair Mechanisms in Atherosclerosis

    Författare :Sara Rattik; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Atherosclerosis; Cardiovascular disease; T helper 2 cells; ApoB100; Regulatory B cells; Regulatory T cells; Smooth muscle cells; IL-22.;

    Sammanfattning : Atherosclerosis is a chronic inflammatory disease characterized by the formation of lipid rich plaques in the arterial wall. Rupture of a plaque results in clinical manifestations such myocardial infarction or stroke. LÄS MER

  5. 5. Interrogating Atherosclerotic Plaque Biology Through Responses to Cardiovascular Risk Management and Imaging

    Författare :Elin Good; Ebo de Muinck; Petter Dyverfeldt; Tiny Jaarsma; Dick Wågsäter; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Atherosclerosis causes more deaths than any other disease worldwide, and the cause of death is most commonly a rupture of a vulnerable atherosclerotic plaque, resulting in a thrombotic event in the heart or brain. The major risk factors for plaque progression are well known, but all the mechanisms that drive atherosclerotic plaques towards catastrophic events are not yet fully elucidated. LÄS MER