Sökning: "c-src kinase"
Hittade 3 avhandlingar innehållade orden c-src kinase.
1. Intracellular components involved in parathyroid sensing of extracellular calcium
Sammanfattning : Parathyroid glands are the primary regulator of extracellular calcium ([Ca2+]e). Ca2+ plays a key role in many fundamental biological processes and is also an essential structural component of the skeleton. The parathyroid chief cells detect small changes in [Ca2+]e and respond by altering the secretion of parathyroid hormone (PTH). LÄS MER
2. Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene
Sammanfattning : The aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription factor that is responsible for the activation of several response genes, of which the best characterised is the CYP1A1 gene. The prototype high affinity ligand for the AhR is the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). LÄS MER
3. Receptor-operated signaling pathways in normal and diabetic pancreatic islet cell function
Sammanfattning : Loss of glucose-dependent insulin release is an early pathogenetic event in human type 2 diabetes. Impaired glucose-mediated insulin secretion from pancreatic islet β-cells leads to insulin deficiency and thus hyperglycemia. LÄS MER