Sökning: "primaquine"

Hittade 3 avhandlingar innehållade ordet primaquine.

  1. 1. Mechanisms of activation of the aryl hydrocarbon receptor by novel inducers of the CYP1A1 gene

    Författare :Maria Backlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :AhR; omeprazole; primaquine; CYP1A1; ligand-independent activation; ligandbinding domain; protein tyrosine kinase; c-src kinase;

    Sammanfattning : The aryl hydrocarbon receptor (AhR) functions as a ligand-activated transcription factor that is responsible for the activation of several response genes, of which the best characterised is the CYP1A1 gene. The prototype high affinity ligand for the AhR is the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). LÄS MER

  3. 2. Malaria in travellers and migrants

    Författare :Andreas Wångdahl; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Malaria is a potentially fatal disease that caused approximately 241 million cases and 627 000 deaths in 2020, most in children in Sub-Saharan Africa. In non-endemic countries, malaria is imported by travellers and migrants and timely management and treatment is crucial. LÄS MER

  4. 3. New strategies and tools for Plasmodium falciparum case management and surveillance in the era of imminent resistance to artemisinin-based combination therapy in Tanzania

    Författare :Lwidiko E Mhamilawa; Andreas Mårtensson; Billy Ngasala; Ulrika Morris; Ib Christian Bygbjerg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Plasmodium falciparum; artemether-lumefantrine; drug resistance; Tanzania; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Artemether-lumefantrine has been an efficacious first line treatment for uncomplicated Plasmodium falciparum malaria in Tanzania since its introduction in 2006. Interest has developed in understanding the observation of high residual PCR determined positivity rates on day 3 after supervised artemether-lumefantrine treatment in the magnitude of almost 30% in previous assessments from 2015 in Bagamoyo district, Tanzania. LÄS MER