Sökning: "bromine"

Visar resultat 21 - 25 av 41 avhandlingar innehållade ordet bromine.

  1. 21. Quantitative NanoSIMS provides subcellular concentration and distribution of oligonucleotide therapeutics

    Författare :Cécile Becquart; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NanoSIMS; Antisense Oligonucleotide; Intracellular concentration;

    Sammanfattning : Antisense oligonucleotides (ASOs) represent a powerful therapeutic modality that can selectively modulate gene expression. However, ASOs face two major hurdles that restrict their use in the clinic. The first issue is delivery of the ASO to a tissue of therapeutic interest while reducing exposure to unrelated tissues. LÄS MER

  3. 22. Controlling function by structure-intermolecular interactions and crystal engineering with N-donor ligands

    Författare :Mohamed I D M Ghazzali; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; OPL; 10 phenanthroline]2 .; single crystal diffraction; intermolecular interactions; crystal engineering; Fe II coordination polymers; Schiff’s bases; porphyrins; intercalation; [ Ru tris-1;

    Sammanfattning : In the solid state regime, crystal engineering based on non-covalent synthesis requires an intuition about the intermolecular forces that can dictate the molecular architecture. Hydrogen bonds have become an instrumental tool in the self assembly and supramolecular chemistry. LÄS MER

  4. 23. Development of methods for determining aflatoxins in biological material

    Författare :Anders Kussak; Rainer Stephany; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Aflatoxins; Mycotoxins; Carcinogen; Airborne dust; Urine; Feed factories; Immunoaffinity extraction; Solid-phase extraction; Post-column derivatization; Electrospray; Mass spectrometry;

    Sammanfattning : In this thesis, it is shown how aflatoxins can be determined in biological material. The thesis is a summary of five papers.Aflatoxins are carcinogenic mycotoxins produced by Aspergillus moulds. Methods were developed for the determination of aflatoxins in samples of airborne dust and human urine collected at feed factories. LÄS MER

  5. 24. Creating Optical Activity: Total Spontaneous Resolution and Viedma Ripening

    Författare :Per Martin Björemark; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Optical activity; absolute asymmetric synthesis; total spontaneous resolution; Viedma ripening; grinding; chirality; conglomerate; coordination compound; coordination polymer; single crystal X-ray diffraction; solvent free oxidation; nantioselective sulfide oxidation; solid state VCD;

    Sammanfattning : The creation of optical activity has been considered as something impossible even though reports of such creation via total spontaneous resolution since the 1940´s have been published. More recently Viedma ripening have been developed that also produce enantiopure bulk product. Both methods are examples of absolute asymmetric synthesis i.e. LÄS MER

  7. 25. Levels of organohalogen compounds in White-tailed sea eagles (Haliaeetus albicilla) in relation to reproduction impairment in the Bothnian Sea

    Författare :Ulrika Nordlöf; Lillemor Asplund; Björn Helander; Yngve Zebuhr; Michael Mclachlan; Roland Kallenborn; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Applied Environmental Science; tillämpad miljövetenskap;

    Sammanfattning : The white-tailed sea eagle (Haliaeetus albicilla) is in the top of the marine food chain and its existence in Sweden has been threatened several times. The species succeeded to recover from the deep decline in the 1970s when the exposure to persistent organic pollutants influenced the reproduction negatively. LÄS MER