Sökning: "Cécile Becquart"

Hittade 1 avhandling innehållade orden Cécile Becquart.

1. 1. Quantitative NanoSIMS provides subcellular concentration and distribution of oligonucleotide therapeutics

   Författare :Cécile Becquart; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NanoSIMS; Antisense Oligonucleotide; Intracellular concentration;

   Sammanfattning : Antisense oligonucleotides (ASOs) represent a powerful therapeutic modality that can selectively modulate gene expression. However, ASOs face two major hurdles that restrict their use in the clinic. The first issue is delivery of the ASO to a tissue of therapeutic interest while reducing exposure to unrelated tissues. LÄS MER