Sökning: "bone formation"

Visar resultat 21 - 25 av 323 avhandlingar innehållade orden bone formation.

1. 21. Peri-implantitis : treatment and effects of enamel matrix derivative

   Författare :Catrine Isehed; Pernilla Lundberg; Anders Holmlund; Leif Jansson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; implant; peri-implantitis; bone regeneration; enamel matrix derivative; surgical treatment; proteome; bone marrow macrophages; osteoclast formation; bone resorption; odontologi; Odontology;

   Sammanfattning : Biological complications affecting osseointegrated dental implants are a growing treatment problem in clinical practice. Since the number of implant carriers has increased in recent decades, this is an urgent topic in dentistry. LÄS MER

3. 22. Bone Enhancement with BMP-2 for Safe Clinical Translation

   Författare :Marta Kisiel; Jöns Hilborn; Monica Wiig; Richard Oreffo; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bone repair; Bone healing; Bone morhogenetic protein-2; Osteogenesis; Extracelular matrix; Hyaluronan; Animal model; Orthopaedics; Ortopedi; Engineering Science with specialization in Materials Science; Teknisk fysik med inriktning mot materialvetenskap;

   Sammanfattning : Bone morphogenetic protein-2 (BMP-2) is considered a promising adjuvant for the treatment of bone regeneration. However, BMP-2 delivery in a conventional collagen scaffold needs a high dose to achieve an effective outcome. Moreover, such dosage may lead to serious side effects. LÄS MER

4. 23. Experimental studies on the effects of insulin-like growth factor I and glucocorticoids on bone metabolism

   Författare :Kenneth B. Jonsson; Uppsala universitet; []
   Nyckelord :Medical sciences; Bone; bone resorption; glucocorticoids; insulin-like growth factor I; osteoblasts; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Osteoporosis is a major cause of disability among patients that are dependent on glucocorticoids in the treatment of inflammatory disease. The pathogenesis behind this side effect is complex, involving dysregulation of hormonal systems and direct effects on bone cells. LÄS MER

5. 24. Allograft bone in hip revision: the effect of locally applied pharmacological treatment

   Författare :Ola Belfrage; Lund Ortopedi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allograft bone; bone transplantation; bisphosphonate; bone morphogenetic proteins; hip revision; radiostereometric analysis;

   Sammanfattning : The clinical success of primary hip replacement is paramount but the need for revisions will continue to increase due to the increasing number of operated individuals. In Sweden, the number of hip revisions in 2012 exceeded 2,300. During implant loosening, some of the bone in the femur is lost, which can make the revision more difficult. LÄS MER

7. 25. On nano size structures for enhanced bone formation

   Författare :Luiz Meirelles; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nano structures; nanotopography; surface modification; osseointegration; bone tissue; titanium implants;

   Sammanfattning : Purpose The general aim of the present thesis was to investigate early bone response to titanium implants modified with nano size structures. Therefore, 1. a model to evaluate titanium implants modified with nano size structures was validated; 2. a suitable detection method of nano size structures was implemented. LÄS MER