Sökning: "angiotensin-converting enzyme"

Visar resultat 26 - 30 av 53 avhandlingar innehållade orden angiotensin-converting enzyme.

  1. 26. Pulmonary ventilation and perfusion assessed by electrical impedance tomography - Experimental studies in pigs

    Författare :Anneli Fagerberg; Göteborgs universitet; []
    Nyckelord :electrical impedance tomography; V Q matching; pig; endotoxinaemic ALI; ACE inhibitor;

    Sammanfattning : Pulmonary ventilation and perfusion and ventilation/perfusion (V/Q) matching determine gas exchange in every lung unit in the healthy state and in the pathologically altered lung. Mismatch of V and Q lead to hypoxaemia and hypercapnia and monitoring of V/Q relations are thus important in critical illness. LÄS MER

  3. 27. Impairment of Endothelial Thromboprotective Function by Haemodynamic and Inflammatory Stress - Implications for hypertensive disease

    Författare :Erik Ulfhammer; Göteborgs universitet; []
    Nyckelord :tissue-type plasminogen activator; endothelium; fibrinolysis; hypertension; shear stress; strain; antihypertensive agents; inflammation; TNF-alpha; NF-kappaB; MAPK;

    Sammanfattning : The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA). The endothelium synthesizes and stores t-PA and regulated release of the enzyme is an important local protective response to prevent thrombus extension. LÄS MER

  4. 28. The renin-angiotensin system in renal tubulogenesis. Experimental studies in the rat

    Författare :Daina Lasaitiene; Göteborgs universitet; []
    Nyckelord :angiotensin II; extracellular matrix; inflammation; mitochondrial biogenesis; renal development; renin-angiotensin system; thick ascending limb of Henle; tubulogenesis;

    Sammanfattning : The kidney and the renin-angiotensin system (RAS) are vital regulators of blood pressure and salt-water balance. In order to appropriately regulate circulatory homeostasis, the kidney must undergo normal development, in which the RAS plays a crucial role. LÄS MER

  5. 29. Heart failure : aspects on treatment and prognosis

    Författare :Märit Mejhert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Heart failure; management program; quality of life; gender; prognosis;

    Sammanfattning : The aim of this thesis was to describe aspects on treatment and prognosis in heart failure. In paper I, we studied two hundred and seventy-nine hospitalised heart failure patients, and related clinical and demograhic data to the use of diagnostic tests, treatment and follow up. LÄS MER

  7. 30. Visualization of Peripheral Pain Generating Processes and Inflammation in Musculoskeletal Tissue using [11C]-D-deprenyl PET

    Författare :Mikko Aarnio; Torsten Gordh; Jens Sörensen; Magnus Peterson; Lars Ståhle; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ankle injuries; arthritis; binding site; binding target; carbon-11; deprenyl; high-throughput screening; inflammation; monoamine oxi-dase; pain; PET; whiplash; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Sammanfattning : An objective visualization and quantification of pain-generating processes in the periphery would alter pain diagnosis and represent an important paradigm shift in pain research. Positron emission tomography (PET) radioligand [11C]-D-deprenyl has shown an elevated uptake in painful inflammatory arthritis and whiplash-associated disorder. LÄS MER