Sökning: "angiotensin-converting enzyme"

Visar resultat 16 - 20 av 53 avhandlingar innehållade orden angiotensin-converting enzyme.

  1. 16. Drug use in the elderly : are quantity and quality compatible

    Författare :Inga Klarin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Population-based; cross-sectional; longitudinal; aged; aged 80 and over; drug utilization; cardiovascular agents; angiotensin-converting enzyme inhibitors; inappropriate drug use; heart failure; dementia; hospitalization; mortality; Sweden.;

    Sammanfattning : The increasing number of elderly, and the increasing drug use among the elderly, emphasizes the need to continuously monitor drug utilization in this group. The scarcity of randomized controlled trials including elderly people give population-based, observational studies an important role as source of information on drug use and drug-related problems. LÄS MER

  2. 17. Genetic Factors Contributing to Hypertension. With Emphasis on Hypertension in Type 2 Diabetes

    Författare :Kristina Bengtsson Boström; diabetes och endokrinologi Genomik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; diabetology; primary care; genetics; Hypertension; type 2 diabetes;

    Sammanfattning : The causes of hypertension (HT) and type 2 diabetes (T2DM) are mainly unknown, but they arise from interplay between several genetic and environmental factors. The aim of this thesis was to investigate whether polymorphisms in putative candidate genes for HT increase the susceptibility to HT and/or T2DM. LÄS MER

  3. 18. Clinical studies in severe heart failure : neurohormonal, electrolyte and metabolic aspects

    Författare :Mats Broqvist; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Congestive heart failure is a common and complex syndrome with a poor prognosis. Although heart disease is usually the primary event, the clinical syndrome is characterised by several extra-cardiac manifestations. Neurohormonal activation seems to play a crucial role for these manifestations and the progression of the disease. LÄS MER

  4. 19. Genetic association analysis of overlapping biological pathways in cardiovascular and Alzheimer disease

    Författare :Hagit Katzov; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Genetic variation; association; ACE; ABCA1; Alzheimer disease; pleiotropy; cardiovascular disease;

    Sammanfattning : To gain insight into the importance of the genome for diseases, sequencing and genotyping efforts aim to identify the consequences of genetic variation on both a functional and population level. The task involves the fine-resolution mapping of biologically significant genes and regions discerned by linkage analysis. LÄS MER

  5. 20. Vascular receptor changes in ischemic stroke

    Författare :Emelie Stenman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vascular receptor changes; Ischemic stroke; Endothelin; Angiotensin; Cardiovascular system; Kardiovaskulära systemet; Pharmacological sciences; pharmacognosy; pharmacy; farmakognosi; farmaci; toxikologi; toxicology; Farmakologi;

    Sammanfattning : The present thesis aimed to examine how ischemic stroke affects the vascular endothelin and angiotensin systems in cerebral arteries. To study vascular receptor changes in ischemic stroke transient focal ischemia was induced in rats. LÄS MER