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Visar resultat 1 - 5 av 73 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Airway epithelial shedding: Morphological and functional aspects in vivo

    Författare :Jonas Erjefält; Luftvägsinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; eosinophils; neutrophils; plasma exudation; barrier restitution; basal cells; ciliated cells; secretory cells; Epithelial repair; epithelial shedding; fibrinogen; fibronectin; Respiratory system; Andningsorganen;

    Sammanfattning : Epithelial damage may contribute to the pathology in airway diseases such as asthma and rhinitis. However, the distribution of epithelial shedding in inflammatory airway diseases and, particularly, the ensuing repair processes are largely unknown. LÄS MER

  2. 2. Allergic airway disease : studies on diesel exhaust exposures, oxylipins and antioxidants

    Författare :Nirina Larsson; Annelie Behndig; Leif Bjermer; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; allergic rhinits; diesel exhaust; airway inflammation; oxylipins; metabolomics; antioxidants; SVCT2; bronchoscopy; lungmedicin; Lung Medicine;

    Sammanfattning : Allergic airway disease, i.e. allergic rhinitis (AR) and asthma, is a common health problem. The prevalence is increasing in most countries of the world. LÄS MER

  3. 3. Genetic determinants of epithelial differentiation in the mouse and human lungs

    Författare :Andreas Liontos; Christos Samakovlis; Robert Rottier; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; airway development; single cell; secretory epithelial cells; SCRINSHOT; facultative stem cells; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Several airway epithelial cell types and subpopulations have been defined, using high throughput single-cell mRNA profiling. However, the spectrum and topology of cell populations within the secretory cell lineage has not been explored. LÄS MER

  4. 4. New aspects of allergic mechanisms and innate immunity in asthma. Alarmins as upstream mediators of asthma inflammation

    Författare :Sangeetha Ramu; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Asthma; Aeroallergens; Airway inflammation; Bronchial epithelial cells; Bronchial smooth muscle cells; Metabolic DAMPs; Proteases; Allergen immunotherapy; Mast cells; Viral infections; innate immunity;

    Sammanfattning : Asthma is a chronic inflammatory lung disease affecting over 300 million individuals worldwide. Both respiratory viral infections and aeroallergens have been identified as important risk factors for asthma. LÄS MER

  5. 5. Interleukin-17 in non-allergic airway inflammation

    Författare :Martti Laan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

    Sammanfattning : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. LÄS MER