Sökning: "adult neural progenitor cell"

Visar resultat 1 - 5 av 60 avhandlingar innehållade orden adult neural progenitor cell.

1. 1. Features of adult neural progenitor cells

   Författare :Lisa Arvidsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :adult neural progenitor cell;

   Sammanfattning : The adult Central Nervous System (CNS) harbors neural progenitor cells (NPCs) in three areas: the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone in the hippocampus and around the central canal in the spinal cord. The NPCs can be isolated and cultured in vitro. LÄS MER

3. 2. Neural stam cells, TLX, and Neuroblastoma

   Författare :Ravi Kanth Rao Saini; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; TLX; Neural Stem Cells; Dedifferentiation; DISC-1; DNA-PKcs;

   Sammanfattning : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. LÄS MER

4. 3. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors

   Författare :Jimmy Larsson; Karin Forsberg-Nilsson; Ola Hermanson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; differentiation; proliferation; migration; PDGF; SCF; NRBP2; medulloblastoma; Biochemistry; Biokemi; Medical Biochemistry; Medicinsk biokemi;

   Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER

5. 4. Modeling Neural Stem Cell and Glioma Biology

   Författare :Tobias Bergström; Karin Forsberg-Nilsson; Staffan Johansson; Sven Påhlman; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neural stem cell; integrins; glioma; PDGF; mast cell; Molekylär cellbiologi; Molecular Cellbiology; Oncology; Onkologi;

   Sammanfattning : This thesis is focused on neural stem cell (NSC) and glioma biology. I discuss how NSCs interact with extracellular matrix (ECM) proteins in the stem cell niche, and investigate the consequences of deregulated Platelet-derived growth factor (PDGF) signaling for embryonic NSCs in transgenic mice. LÄS MER

7. 5. Functionalization and characterization of surface supported lipid membranes and their application in cell culture

   Författare :Dorota Thid; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cell - surface interaction; supported phospholipid bilayer; IKVAV; DHA; stem progenitor cells; neural cells; surface analytical techniques; QCM-D; surface functionalization; peptide; cell differentiation; cell attachment; membrane; fatty acid;

   Sammanfattning : Phospholipid bilayers supported on a solid surface constitute a versatile, biomimetic platform for a variety of applications, such as biosensing, drug delivery research, cell engineering and as cell membrane mimics in fundamental cell research. Phosphocholine supported lipid bilayers are resistant to cell attachment in a wide range of conditions, and can be functionalized with bioactive signaling molecules to promote specific interactions with cells. LÄS MER