Sökning: "Toll-like receptors"

Visar resultat 36 - 40 av 96 avhandlingar innehållade orden Toll-like receptors.

  1. 36. Function and Regulation of B-cell Subsets in Experimental Autoimmune Arthritis

    Författare :Anna-Karin E. Palm; Sandra Kleinau; Susanna Cardell; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; B cells; marginal zone; autoimmune arthritis; spleen; lymph node; antigen presentation; Fc gamma receptor IIb; complement receptors 1 and 2; mast cells; Biologi med inriktning mot molekylär immunologi; Biology with specialization in Molecular Immunology;

    Sammanfattning : B lymphocytes play a significant role in autoimmune arthritis, with their function stretching beyond autoantibody production to cytokine secretion and presentation of autoantigen. However, the involvement and activation of different B-cell subset in the autoimmune response is not fully clear. LÄS MER

  3. 37. Microbial regulation of PPARgamma : nuclear receptor networks important for colonic homeostasis

    Författare :Linda Aronsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : One of the central issues surrounding the physiology of good health is to uncover and understand the molecular networks responsible for its maintenance. The alimentary tract in particular, demands a properly sustained homeostatic control since it is constantly challenged by potentially harmful agents along with innocuous nutrients, with the burden of basic metabolic functions in its ward. LÄS MER

  4. 38. Monocyte and Neutrophil Inflammatory Responses to the Periodontopathogen Porphyromonas gingivalis

    Författare :Kartheyaene Jayaprakash; Torbjörn Bengtsson; Allan Sirsjö; Hazem Khalaf; Anders Johansson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; Neutrophils; Porphyromonas gingivalis; Gingipains; Biomedicin; Biomedicine;

    Sammanfattning : Periodontitis is one of the most common adult infections. Duing bacteremia in healthy individuals or patients with chronic periodontitis, a number of oral bacteria such as Porphyromonas gingivalis encounter inflammatory cells in the blood eg. platelets, neutrophils and monocytes. LÄS MER

  5. 39. Recognition and clearance of Streptococcus pneumoniae by the innate immune system

    Författare :Katharina Beiter; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae (the pneumococcus) is a major human pathogen causing diseases such as pneumonia, bacteremia or meningitis and constitutes a leading cause of morbidity and mortality worldwide. The pathogenesis of pneumococcal disease and the mechanisms of recognition and clearance of S. LÄS MER

  7. 40. Leukocyte responses to pathogens : integrins, membrane rafts and nitric oxide

    Författare :Martin Winberg Tinnerfelt; Birgitta Rasmusson; Maria Lerm; Eva Särndahl; Hans Tapper; Håkan Eriksson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : During microbial invasion, leukocytes of the innate immunity are rapidly recruited to the site of infection where they internalize (phagocytose), kill and digest the invaders. To aid this process, leukocytes express surface receptors such as Toll-like receptors, β2-integrins and Fc-receptors. LÄS MER