Sökning: "Th1"

Visar resultat 31 - 35 av 260 avhandlingar innehållade ordet Th1.

  1. 31. Leishmania and HIV-1 interaction : immunopathogenic mechanisms

    Författare :Dawit Wolday; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Both Leishmania and HIV can infect and multiply in macrophages, and both can dysregulate the T-helper (Th) immune system. This thesis was, therefore, undertaken to unravel some of the underlying immunopathogenic mechanisms of the interaction of the two pathogens. LÄS MER

  3. 32. Immunotherapy and COX-2 inhibition against malignant brain tumors

    Författare :Sofia Eberstål; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant brain tumors; immunotherapy; IFN-γ; GM-CSF; COX-2 inhibition;

    Sammanfattning : Glioblastoma multiforme (GBM) is the most common primary brain tumor in the central nervous system and the prognosis is very poor despite conventional therapies including surgery, chemo- and radiotherapy. Peripheral vaccination with irradiated tumor cells represent a novel therapy that targets both dividing and non-dividing tumor cells and minimizes the risk of therapy resistance by presenting multiple tumor antigens. LÄS MER

  4. 33. Immunopathogenic aspects of resolving and progressing appendicitis

    Författare :Marie Rubér; Christina Ekerfelt; Roland Andersson; Gunnar Olaison; Johan Rönnelid; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Background: Appendicitis is one of the most common diseases requiringemergency surgical intervention. There are several indications that the diagnosisappendicitis harbours two different entities, one progressing to gangrene and perforation(advanced) and one that resolves spontaneously (phlegmonous). LÄS MER

  5. 34. Cytokine responses in human Lyme borreliosis : The role of T helper 1-like immunity and aspects of gender and co-exposure in relation to disease course

    Författare :Sara Jarefors; Christina Ekerfelt; Pia Forsberg; Jan Enerudh; Chatarina Svanborg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Borrelia; human granulocytic anaplasmosis; cytokine; immunology; chronic; Clinical immunology; Klinisk immunologi;

    Sammanfattning : Lyme borreliosis was first described some 30 years ago in the USA. Today, it is the most common vector borne disease in Europe and the USA. The disease can have multiple stages and symptoms can manifest from various parts of the body; joints, skin heart and nervous system. In Europe, neuroborreliosis is the most frequent late stage diagnosis. LÄS MER

  7. 35. Immune maturation and modulation in childhood allergies : Aspects of epigenetic, mucosal and systemic immune mediators in allergy development and prevention

    Författare :Johanna Huoman; Maria Jenmalm; Lennart Nilsson; Petra Ina Pfefferle; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The prevalence of allergic diseases has in the past century increased among children in affluent societies. Underlying causes are incompletely disentangled, but decreased diversity in environmental and microbial exposures could drive allergy development. LÄS MER