Sökning: "Scan statistic"

Hittade 4 avhandlingar innehållade orden Scan statistic.

1. 1. Extreme Value Analysis of Huge Datasets: Tail Estimation Methods in High-Throughput Screening and Bioinformatics

   Författare :Dmitrii Zholud; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Extreme Value Statistics; High-Throughput Screening; HTS; Bioinformatics; analysis of huge datasets; quality control; correction of theoretical p-values; comparison of pre-processing methods; SmartTail; estimation of False Discovery Rates; test power; distribution tail; high level excursions; quantile estimation; multiple testing; Student t−test; Welch statistic; small sample sizes; F−test; Wiener process; Gaussian random walk; Shepp statistic; limit theorems; exotic options.; estimation of False Discovery Rates;

   Sammanfattning : This thesis presents results in Extreme Value Theory with applications to High-Throughput Screening and Bioinformatics. The methods described here, however, are applicable to statistical analysis of huge datasets in general. The main results are covered in four papers. LÄS MER

3. 2. Scan Statistics for Space-Time Cluster Detection

   Författare :Benjamin Allévius; Martin Sköld; Michael Höhle; Paula Moraga-Serrano; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : Scan statistics are used by public health agencies to detect and localize disease outbreaks. This thesis provides an overview of scan statistics in the context of prospective disease surveillance and outbreak detection, presents a novel scan statistic to deal with the type of zero-abundant data that is often encountered in these settings, and—perhaps most importantly—implements this and other scan statistics in a freely available and open source R package. LÄS MER

4. 3. Epidemiological studies including new methods for cluster analysis of acute childhood leukaemia and brain tumours in Sweden

   Författare :Ulf Hjalmars; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Epidemiology; childhood; leukaemia; brain tumours; geographical information systerns; cluster analysis; Scan statistic; Knox test; environmental factors;

   Sammanfattning : Background: The aetiology in childhood cancer is essentially unknown. Epidemiological investigations as to whether the incidence rates have changed for paediatric cancers or whether clustering of cases occur may give clues to possible causal factors. LÄS MER

5. 4. Anisotropic mechanical behaviors and microstructural evolution of thin-walled additively manufactured metals

   Författare :Cheng-Han Yu; Johan Moverare; Ru Lin Peng; Joe Kelleher; Linköpings universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; hot tensile testing; slow strain rate tensile testing; creep; anisotropy; crystallographic texture evolution; deformation twinning; Varmdragprov; Dragprov med låg töjningshastighet; kryp; anisotropi; kristallografisk textur; deformationstvillingar;

   Sammanfattning : Additive manufacturing (AM), also known as 3D printing, is a concept and method of a manufacturing process that builds a three-dimensional object layer-by-layer. Opposite to the conventional subtractive manufacturing, it conquers various limitations on component design freedom and raises interest in various fields, including aerospace, automotive and medical applications. LÄS MER