Sökning: "Recombinant Vaccine"
Visar resultat 1 - 5 av 83 avhandlingar innehållade orden Recombinant Vaccine.
1. Heat shock proteins as vaccine adjuvants
Sammanfattning : New efficient vaccines against infectious diseases are in demand. Some important factors impeding the vaccine development are the poor immunogenicity and the MHC restriction of the immune responses to a number of antigens. LÄS MER
2. Recombinant subunit vaccines : protein immunogens
Sammanfattning : Recombinant techniques provide valuable tools for thedevelopment of modern subunit vaccines. In this thesisdifferent systems for production of recombinant subunitvaccines are presented. The strategies investigated includeprotein immunogens, live bacterial vectors and nucleicacids. LÄS MER
3. Development of a New Oral Vaccine against Diphtheria and the Study of its Immunogenicity in Mouse and Man
Sammanfattning : Most pathogens enter the body via mucosal surfaces. In contrast to parenterally administered vaccination, mucosal vaccination has the advantage of eliciting both a systemic and a local mucosal immune response. An oral biodegradable adjuvant with these features would have great potential. LÄS MER
4. Production and delivery of recombinant subunit vaccines
Sammanfattning : Recombinant strategies are today dominating in thedevelopment of modern subunit vaccines. This thesis describesstrategies for the production and recovery of protein subunitimmunogens, and how genetic design of the expression vectorscan be used to adapt the immunogens for incorporation intoadjuvant systems. LÄS MER
5. Development of a recombinant protein vaccine against Plasmodium falciparum malaria
Sammanfattning : Malaria, caused by Plasmodium falciparum is one of the world´s deadliest diseases, killing one to two million children, while another 500 million suffer from clinical attacks every year. Infections caused by P. LÄS MER