Sökning: "Mikael Ljungdahl"

Hittade 2 avhandlingar innehållade orden Mikael Ljungdahl.

1. 1. The small intestine in experimental peritonitis : An experimental study focusing om intestinal energy metabolism, bacterial translocation and mucosal immunology

   Författare :Mikael Ljungdahl; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Bacterial translocation; endotoxin; faecal peritonitis; high-energy phosphates; hypoxia; intramucosal pH; IL-6; ischaemia; lactate; lymphocytes; mucosal injury; oxygendelivery; pigs; sepsis; tonometry; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

   Sammanfattning : The gut is highly susceptible to injury during sepsis. An impaired mucosal barrier permitstranslocation of enteric microorganisms to blood or other organs. In a porcine model sepsiswas induced by faecal peritonitis. LÄS MER

3. 2. Inflammatory Reactions in Peritonitis and Malignant Obstructive Jaundice : Clinical and Experimental Studies with Special Emphasis on the Cellular Immune Response

   Författare :Johanna Österberg; Ulf Haglund; Mikael Ljungdahl; Roland Andersson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; CLP; sepsis; peritonitis; bacterial translocation; malignant obstructive jaundice; Linomide; COX inhibitor; SC-236; indometacin; T lymphocyte; macrophage; mucosa; MLN; gut immune cell distribution; mucosal injury; cytokines; TNF-α; IL-6; IL-10; endotoxin; caspase-3; apoptosis; Kirurgi; Surgery; Kirurgi;

   Sammanfattning : Patients with peritonitis or malignant obstructive jaundice (HPB+) have an increased morbidity and mortality due to sepsis. An altered cell-mediated immunity in the intestinal mucosa might promote gut barrier failure, increased endotoxin and cytokine release and bacterial translocation (BT) in these conditions. LÄS MER