Sökning: "Peter Brzezinski"

Visar resultat 11 - 15 av 23 avhandlingar innehållade orden Peter Brzezinski.

  1. 11. Role of respiratory supercomplexes : Electronic connection between complexes III and IV

    Författare :Agnes Moe; Peter Brzezinski; James A. Letts; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; electron transfer; cytochrome c oxidase; cytochrome bc1; respiratory supercomplex; bioenergetics; membrane protein; biokemi; Biochemistry;

    Sammanfattning : In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. LÄS MER

  3. 12. Cytochrome c Oxidase dysfunction in cancer : Exploring the molecular mechanisms

    Författare :Ida Namslauer; Peter Brzezinski; Susanne Arnold; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Sammanfattning : Mutations in genes encoding the mitochondrial enzyme Cytochrome c Oxidase (CytcO) have lately been found in connection to various types of cancer. Some mutations result in substitutions of highly conserved amino-acid residues. LÄS MER

  4. 13. Protein and lipid interactions within the respiratory chain : Studies using membrane-mimetic systems

    Författare :Tobias Nilsson; Peter Brzezinski; Petra Hellwig; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; ATP synthase; Bioenergetics; membrane-mimetics; Rcf1; liposomes; oxidative phosphorylation; lipids; protein-protein interactions; Biochemistry; biokemi;

    Sammanfattning : Energy conversion from nutrients to ATP is a vital process in cells. The process, called oxidative phosphorylation (OXPHOS) is performed by a combination of membrane-bound proteins. These proteins have been studied in great detail in the past, however much is still unknown about how they interact with each other. LÄS MER

  5. 14. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes

    Författare :Gustav Nordlund; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; membrane proteins; method development; respiration; reconstitution; supported membranes; SNAREs; liposome fusion; lipid-protein interactions; Biochemistry; biokemi;

    Sammanfattning : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. LÄS MER

  7. 15. Membrane effects on proton transfer in cytochrome c oxidase

    Författare :Linda Näsvik Öjemyr; Peter Brzezinski; Anthony G. Lee; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cytochrom c oxidase; lipids; membrane; proton transfer; Biochemistry; biokemi;

    Sammanfattning : The biological membrane is composed of lipids and proteins that make up dynamic barriers around cells and organelles. Membrane-spanning proteins are involved in many key processes in the cell such as energy conversion, nerve conduction and signal transduction. LÄS MER