Sökning: "liposome fusion"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden liposome fusion.

  1. 1. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes

    Författare :Gustav Nordlund; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Lipids; membrane proteins; method development; respiration; reconstitution; supported membranes; SNAREs; liposome fusion; lipid-protein interactions; Biochemistry; biokemi;

    Sammanfattning : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. LÄS MER

  3. 2. Bilayer Discs - Fundamental Investigations and Applications of Nanosized Membrane Models

    Författare :Emma Johansson; Katarina Edwards; Mats Almgren; Sven Engström; Uppsala universitet; []
    Nyckelord :Chemistry; disc; threadlike micelle; liposome; model membrane; drug partitioning; cryo-TEM; Kemi;

    Sammanfattning : The bilayer disc is a flat, lipid aggregate structure in the nanometre regime. It is composed of a bilayer of amphiphilic molecules with micelle-forming amphiphilic molecules supporting the rim, which prevent disc fusion and self-closure. LÄS MER

  4. 3. Modification and Utilization of Nanotube-vesicle Networks

    Författare :Martin Markström; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nanotechnology; diffusion; network; nanotube; biomimetic; hydrogel; vesicle; compartmentalization; poly N-isopropyl acrylamide ; Marangoni; liposome;

    Sammanfattning : Methods based on self-assembly and self-organization for construction of lipid bilayer networks, consisting of vesicles (3-100 μm in diameter) connected by conduits (50-300 nm in diameter), have previously been developed. Control over network geometry, topology, content, and membrane composition has been demonstrated. LÄS MER

  5. 4. On the Formation of Supported Phospholipid Bilayers

    Författare :Erik Reimhult; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; vesicle adsorption; formation kinetics; SPR; QCM-D; SPB; AFM; supported lipid bilayer; supported membrane; liposome;

    Sammanfattning : Lipid bilayers are a central component of both the structure and function of biological membranes, like the one surrounding cells of living organisms. Since the lipid bilayer provides a host matrix for membrane proteins, which perform many of the specialized tasks in cells like energy, signal and material transduction, researchers have tried to develop artificial model membranes to study a variety of membrane protein functions. LÄS MER

  7. 5. Studying the influence of the physicochemical properties of lipid nanoparticles for mucosal vaccine delivery

    Författare :Karin Norling; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; influenza; nanoparticles; CTA1-DD; liposomes; dendritic cells; lipodisks; antigen presentation; flow cytometry; vaccine carriers; TIRF microscopy;

    Sammanfattning : Lipid-based nanoparticles have attracted attention as promising pharmaceutical carriers. Reports of them having inherent adjuvant properties make them particularly interesting as vaccine vectors; however, the physicochemical profile of an ideal nanoparticle for mucosal vaccine delivery remains unknown. LÄS MER