Sökning: "Pertussis"

Visar resultat 16 - 20 av 43 avhandlingar innehållade ordet Pertussis.

  1. 16. Insulin-like growth factor-II : cellular effects through different receptors

    Författare :Qimin Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Insulin-like growth factor-II (IGF-II) and IGF-I are single-chain polypeptides structurally homologous to proinsulin and share similarities with insulin in functional characteristics. Cellular actions of IGF-II are generally thought to be mediated through the IGF-I or insulin receptors, but not the IGF-II receptor, which is a single chain protein, identical to the cation independent mannose 6-phosphate (M6P) receptor and responsible for lysosomal enzyme targeting and degradation of IGF-II. LÄS MER

  3. 17. Anti-diabetic and anti-inflammatory effects of medicinal plants in a type 2 diabetic animal model

    Författare :Ezarul Faradianna Lokman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 2 diabetes;

    Sammanfattning : Medicinal plants have been suggested since ancient times to be a good source of drugs for treating diabetes. The aims of this thesis were to identify the anti-diabetic effects and to understand further the mechanisms involved for two traditional plants, borapetol B (C1) isolated from Tinospora crispa, and Gynostemma pentaphyllum (GP), in diabetic rats. LÄS MER

  4. 18. Cost-Effectiveness of Vaccination and the Value of Prevention

    Författare :Ellen Wolff; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Health Econmics;

    Sammanfattning : The overall aim of this thesis was to analyse the cost-effectiveness of vaccination of infectious diseases and to investigate the value of prevention, in a Swedish setting. This thesis consists of five studies. LÄS MER

  5. 19. Identification and Characterization of Biomarkers in Bacterial Infections

    Författare :Martin Storm; Lars Engstrand; Ann-Christine Syvänen; Hans-Jurg Monstein; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; Microbiology; Bacteriology; Chlamydia trachomatis; Bordetella perussis; Helicobacter pylori; Real-Time PCR; Microarray; Antigenome; Vaccine; Biomarker; Mikrobiologi; Microbiology; immunology; infectious diseases; Mikrobiologi; immunologi; infektionssjukdomar;

    Sammanfattning : In recent years molecular biology has become an integral part of the clinical laboratory. With an ever increasing number of methodologies and applications being presented each year it has increased our knowledge of how bacteria cause disease as well as our ability to predict disease outcome. LÄS MER

  7. 20. Assessment of anti-diabetic effect of Vietnamese herbal drugs

    Författare :Nguyen Khanh Hoa; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :G-protein; type 2 diabetes; phanoside; antidiabetic plant; hypoglycemic agent; insulin secretion; pancreatic islets; Gynostemma pentaphyllum; Anemarrhena asphodeloides; Angiopteris evecta;

    Sammanfattning : The prevalence of type 2 diabetes mellitus is increasing in Vietnam as well as in other developing countries (China, Indian subcontinent, and Africa). Searching for hypoglycemic agents with origin from domestic herbals was considered as a useful way to find novel therapy of the disease. After treatment i.p. LÄS MER