Sökning: "Early onset"

Visar resultat 1 - 5 av 633 avhandlingar innehållade orden Early onset.

  1. 1. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study

    Författare :Ewa Berglin; Solbritt Rantapää-Dahlqvist; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER

  2. 2. Early rheumatoid arthritis : biomarkers and hormonal factors in relation to disease progression

    Författare :Antonia Boman; Solbritt Rantapää-Dahlqvist; Ewa Berglin; Gerd-Marie Alenius; Mikael Brink; Heidi Kokkonen; Inger Gjertsson; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Early rheumatoid arthritis; biomarker; ACPA; RANKL; disease activity; radiological destruction; cardiovascular events; hormonal factors; reumatologi; rheumatology;

    Sammanfattning : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease, affecting approximately 0.5 to 1% of the adult population. Although the aetiology is not fully known, a complex interaction between genetic, environmental and stochastic factors is thought to trigger the pathogenic mechanisms. LÄS MER

  3. 3. Genetic Alterations in Early Onset Breast Cancer

    Författare :Massimiliano Gentile; Anne-Lise Börresen-Dale; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Cancer is in essence a genetic disease, brought about by an accumulation of alterations in genes that encode proteins responsible for the control of cell growth, cell death and the maintenance of genomic integrity. Recent years have seen the unravelling of numerous genes that are targeted in carcinogenesis. LÄS MER

  4. 4. Insomnia: psychological mechanisms and early intervention : a cognitive-behavioral perspective

    Författare :Markus Jansson; Steven J. Linton; Lars-Gunnar Lundh; Örebro universitet; []
    Nyckelord :SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; Psychology; insomnia; development; distress; worry; early intervention; cognitive-behavioral therapy; dysfunctional beliefs and attitudes about sleep; Psykologi; Psychology; Psykologi; Psychology; Psykologi;

    Sammanfattning : This dissertation focused on the role of psychological mechanisms in the development of insomnia and the effectiveness of an early cognitive-behavioral intervention for insomnia. The first aim was to examine whether distress, worry, and dysfunctional beliefs and attitudes about sleep were related to the development of insomnia. LÄS MER

  5. 5. Unguja Ukuu on Zanzibar : An archaeological study of early urbanism

    Författare :Abdurahman Juma; Paul Sinclair; Chapurukha M Kusimba; Uppsala universitet; []
    Nyckelord :HUMANITIES; HUMANIORA; HUMANIORA; HUMANITIES; Archaeology; cultural complexity; cycles; early urbanism; and urban characterization; Arkeologi; Archaeology subjects; Arkeologiämnen;

    Sammanfattning : This study describes archaeological excavations carried out at Unguja Ukuu on the main island of Zanzibar, Tanzania. The site has long remained obscure, oral histories do not mention it and no particular group among the living community of the island describes its origin from the site. LÄS MER