Sökning: "PMNL"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet PMNL.

  1. 1. Towards a Refined Model of Neutrophil Motility

    Författare :Vesa-Matti Loitto; Karl-Eric Magnusson; Tommy Andersson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human polymorphonuclear leukocytes. PMNL; neutrophils; neutrophil motility; N-formyl-Met-Leu-Phe; Medical microbiology; Medicinsk mikrobiologi;

    Sammanfattning : The ability of human polymorphonuclear leukocytes (PMNL; neutrophils), to sense and move to sites of infection is essential for our defense against pathogens. Cell motility is critically dependent on a dynamic remodeling of morphology. LÄS MER

  3. 2. Human cytomegalovirus (HCMV) infection in patients with inflammatory bowel diseases (IBD) : role in pathogenesis and autoimmunity

    Författare :Afsar Rahbar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human cytomegalovirus; Inflammatory bowel diseases; auto-antibodies; blood platelets; PMNL;

    Sammanfattning : Human cytomegalovirus (HCMV) is one of eight members of the herpesvirus family that infects humans. Like other herpes viruses, HCMV establishes a latent infection after the primary infection, and reactivation may occur later in life. LÄS MER

  4. 3. Mediator synergism in mast celldependent inflammation : role of histamine for leukocyte recruitment

    Författare :Henrik Thorlacius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Chemoattractants; dexamethasone; histamine; inflammation; intravital microscopy; mast cells; leukocyte adhesion; leukocyte rolling; microcirculation; mast cells; nitric oxide; leukotrienes; P-selectin.;

    Sammanfattning : The aim of the present thesis was to study functional interactions between histamine and chemotactic mediators, and the role of histamine for leukocyte recruitment in mast cell-dependent inflammation. Leukocyte rolling, adhesion and emigration. LÄS MER

  5. 4. Mineral fibers, cigarette smoke, and oxidative DNA damage : An experimental study

    Författare :Per Leandersson; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : This study concerns the ability of mineral fibers and cigarette smoke to generate reactive oxygen metabolites and to cause damage to DNA. The generation of hydroxyl radicals (OH") was demonstrated by using the DNA base, deoxyguanosine (dG) as a trapping agent for OH" and determining its hydroxylation to 8-hydroxydeoxyguanosine (80HdG), and oxidative DNA damage was assessed as formation of 80HdG in isolated DNA or in DNA of human lung cells in culture. LÄS MER

  7. 5. Sexually transmitted infections: serological, microbiological and microscopical aspects

    Författare :Matilda Berntsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; herpes simplex virus; seroprevalence; Epstein-Barr virus; cytomegalovirus; urethritis; cervicitis; STI;

    Sammanfattning : The prevalence of sexually transmitted infections (STI) is high in the adult populations world-wide but varies between populations and time periods. Since a high proportion of infected individuals are asymptomatic, diagnostic approaches to reduce further transmission and complications are essential. LÄS MER