Sökning: "neutrophil motility"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden neutrophil motility.
1. Towards a Refined Model of Neutrophil Motility
Sammanfattning : The ability of human polymorphonuclear leukocytes (PMNL; neutrophils), to sense and move to sites of infection is essential for our defense against pathogens. Cell motility is critically dependent on a dynamic remodeling of morphology. LÄS MER
2. Signaling capacity of ß2-integrins in relations to neutrophil motility
Sammanfattning : The neutrophil granulocyte is one of the most mobile cell types in the human body and represents the first line of defense against invading pathogens. Adhesion and chemotactic receptors on the cell surface work together through modulations of the cytoskeleton and thereby cause the cell to move. LÄS MER
3. Functions of integrin receptors in extravascular neutrophil migration and respiratory burst
Sammanfattning : Leukocytes circulate in the vasculature, but, must leave the blood stream and migrate through the surrounding tissue to exert their protective functions in inflammation. Numerous studies have revealed that intravascular leukocyte-endothelial cell interactions involve functions of adhesion molecules belonging to the selectin and integrin receptor families. LÄS MER
4. Obesity, Adipocytes and Breast Cancer – Insights from Translational Studies
Sammanfattning : Background: Being overweight is becoming the new normal, and more than half of the adult Swedish population is overweight which poses a risk to public health. Overweight and obese women have both an increased risk and a worse prognosis for breast cancer, compared with women of normal weight. LÄS MER
5. Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease
Sammanfattning : Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased nitric oxide (NO) generation in the gut lumen and dysfunction in regulation of leukocyte recruitment from the blood stream towards the affected tissue. LÄS MER