Sökning: "leukocyte adhesion"

Visar resultat 1 - 5 av 78 avhandlingar innehållade orden leukocyte adhesion.

  1. 1. Role of adhesion molecules and chemokines in TNF-alpha-induced leukocyte recruitment

    Författare :Xiao Wei Zhang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; intravital microscopy; microcirculation; inflammation; adhesion; leukocyte; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Sammanfattning : Migration of leukocytes from the circulating blood into the extravascular tissue is a key component in inflammatory reactions. Leukocyte extravasation (rolling-activation-adhesion-transmigration) is strictly coordinated by adhesion molecules and chemokines expressed on cell surfaces and in tissues. LÄS MER

  3. 2. Endothelial-leukocyte interactions

    Författare :Maria Olofsson; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histology; endothelial cell; leukocyte; apoptosis; mitochondria; heparin binding protein; vascular permeability; E-selectin; migration; rolling; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. LÄS MER

  4. 3. On leukocyte recruitment in endotoxemic liver injury

    Författare :Daniel Klintman; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ortopedi; traumatology; Kirurgi; orthopaedics; Surgery; Sepsis; Liver; Inflammation; Adhesion; Endotoxemia; traumatologi;

    Sammanfattning : Leukocyte recruitment is a key feature of liver injury associated with endotoxemia and systemic inflammation. The aim of this thesis was to define the adhesive mechanisms underlying leukocyte endothelial cell interactions, and the therapeutic potential of interference with specific adhesion molecules in endotoxemic liver damage. LÄS MER

  5. 4. Regulation of leukocyte integrin adhesiveness

    Författare :Håkan Hedman; Erik Lundgren; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphocytes; Cell Adhesion; Integrins; LFA-1; VLA-4; ICAM-1; VCAM-1; Microvesicles; Protein Kinases; Protein Phosphatases;

    Sammanfattning : .... LÄS MER

  7. 5. On the role of mast cells in chemokine-induced leukocyte recruitment

    Författare :Yusheng Wang; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chemokines; mast cells; TNF-alpha; dexamethasone; P-selectin; E-selectin; activation; Medicine human and vertebrates ; endothelial cells; adhesion; Neutrophil; Medicin människa och djur ; recruitment;

    Sammanfattning : Leukocyte recruitment is considered to playa key role in numerous inflammatory diseases. Tissue accumulation of Jeukocytes is a multi-steps process comprising rolling, adhesion and transmigration. LÄS MER