Sökning: "Oto-Rhino-Laryngology"

Visar resultat 26 - 30 av 38 avhandlingar innehållade ordet Oto-Rhino-Laryngology.

  1. 26. Round window membrane and delivery of biologically active agents into the cochlea

    Författare :Amanj Saber; Mats Ulfendahl; Lars Lundman; Karolinska Institutet; Karolinska Institutet; Sweden Stockholm Karolinska Institutet Department of Clinical Neoruscience; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery; Oto-rhino-laryngologi; Oto-Rhino-Laryngology; Biology; Biologi; Round window membrane; sodium hyaluronate; chitosan; local cochlear drug delivery and gene delivery;

    Sammanfattning : Establishing efficient methods for local administration of drugs to the inner ear has great clinical relevance for the management of inner ear disorders. However, the administration route remains a critical issue. LÄS MER

  3. 27. Clinical investigation and application of Artificial Intelligence in diagnosis and prognosis of squamous cell carcinoma of the head and neck

    Författare :Amir M. Salehi; Karin Nylander; Lena Norberg-Spaak; Wojciech Golusinski; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SCCHN; SCCOT; Recurrence; ML; PET CT; mRNA; transcriptomic; proteomic; Diabetes; AI; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Background: In Sweden around 1400 people are affected by head and neck cancer each year, and around 400 of these tumours are located in the mobile tongue (SCCOT). A major problem with these tumours is the high degree of relapse. LÄS MER

  4. 28. Mapping viruses in non-malignant tonsils, nasal polyps, sinonasal inverted papilloma and laryngeal cancer

    Författare :Alexandra Schindele; Katarina Olofsson; Karin Nylander; Annika Allard; Lalle Hammarstedt Nordenvall; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papilloma virus; Epstein-Barr virus; Human cytomegalovirus; Human adenovirus; p16 tumor suppressor protein; Non-malignant tonsillar disease; Chronic rhino sinusitis with nasal polyps; sinonasal inverted papilloma; laryngeal cancer; EBER-ISH; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Background: The upper respiratory tract is exposed to viruses, which can lead to infection and cancer development. We chose to study common and/or chronic diseases along with common and cancer related viruses in the upper airway. LÄS MER

  5. 29. Neuromuscular injuries and pharyngeal dysfunction in snorers and sleep apnea patients : a study on pathological changes in the human soft palate and its relationship with swallowing dysfunction

    Författare :Farhan Shah; Per Stål; Sture Forsgren; Diana Berggren; Eva Svanborg; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Axons; BDNF; desmin; dystrophin; obstructive sleep apnea; OSA; pharyngeal function; muscle; myopathy; neuropathy; Schwann cells; swallowing dysfunction; upper airway; Medical Cell Biology; medicinsk cellbiologi; oto-rhino-laryngologi; Oto-Rhino-Laryngology; patologi; Pathology; molecular cell biology; molekylär cellbiologi;

    Sammanfattning : Obstructive sleep apnea (OSA) is a prevalent progressive sleep disorder with serious negative health consequences. Although several risk factors such as obesity can make an individual vulnerable to develop OSA, the pathophysiological mechanism for the collapse of the upper airway is unclear. LÄS MER

  7. 30. Pediatric Obstructive Sleep Apnea : Evaluation of surgical treatments and immunological aspects

    Författare :Isabella Sjölander; Danielle Friberg; Johan Hellgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstructive sleep apnea; pediatric sleep disordered breathing; tonsillar surgery; Polysomnography; adenotonsillotomy; adenotonsillectomy; Strength and Difficulties Questionnaire; OSA-18; Oto-Rhino-Laryngology; Oto-rhino-laryngologi;

    Sammanfattning : Pediatric obstructive sleep apnea (OSA) is a sleep-related breathing disorder often caused by  enlargement of the adenoid and the tonsils. The peak prevalence is among children who are two to six years of age, when the lymphatic tissue is  most active. Clinical diagnosis can be challenging, since the symptoms are often unspecific. LÄS MER