Sökning: "Karin Nylander"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden Karin Nylander.
1. Oral lichen planus : studies of factors involved in differentiation, epithelial mesenchymal transition and inflammation
Sammanfattning : Background: Lichen planus is a chronic inflammation of skin and mucosa with unknown cause. Oral Lichen Planus, OLP, affects around 2% of the population. Autoimmunity has been suggested as a possible cause as the disease has autoimmune features such as female predominance, cyclic nature and cytotoxic T-cell infiltrate. LÄS MER
2. Squamous cell carcinoma of the oral tongue : studies of biomarkers connected to human papillomavirus infection, epithelial to mesenchymal transition and locoregional metastatis
Sammanfattning : Background: Oral Tongue Squamous Cell Carcinoma (OTSCC) is the most frequent and aggressive carcinoma in the head and neck region. Its incidence has increased during the last decades, especially in young patients (≤40 years) mainly female. LÄS MER
Sammanfattning : Squamous cell carcinoma of the head and neck (SCCHN), the 6th most common cancer worldwide, has a low 5-year survival. Disease as well as treatment often causes patients severe functional and aesthetic problems. LÄS MER
Sammanfattning : Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa and also one of the more common mucosal conditions mostly affecting middle aged individuals. Even though OLP is well investigated the etiology of this disease is still unknown, even if autoimmunity as a possible etiologic factor has been suggested. LÄS MER
5. p63 and epithelial homeostasis : studies of p63 under normal, hyper-proliferative and malignant conditions
Sammanfattning : Background: The p63 gene is a member of the p53 transcription factor family and can produce six different proteins using two promoters and differential splicing. Expression of p63 is required for proper formation of epithelial tissues. LÄS MER