Sökning: "Norepinephrine"

Visar resultat 21 - 25 av 76 avhandlingar innehållade ordet Norepinephrine.

  1. 21. Control of fatty acid utilization in brown adipose tissue

    Författare :Jan Nedergaard; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : In order to keep warm in cold surroundings, mammals have developed a mechanism for non-shivering thermogenesis. The major part of this heat production takes place in brown adipose tissue. The heat results from combustion of fatty acids. LÄS MER

  3. 22. Levosimendan in early experimental sepsis: effects on the heart and hepatosplanchnic circulation

    Författare :Doris Cunha Goncalves; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; septic shock; myocardial oxygen consumption; myocardial dysfunction; levosimendan; endotoxin; contractility; catecholamines; calcium sensitizer; cardiotonic agents; splanchnic perfusion;

    Sammanfattning : Sepsis-related cardiovascular dysfunction associated with fluid-unresponsive tissue hypoperfusion might require inotropic treatment. This cardiovascular dysfunction seems to involve calcium desensitization and adrenergic unresponsiveness. LÄS MER

  4. 23. The Role of Angiotensin II in Experimental Acute Kidney Injury and Cardiorenal Failure

    Författare :Sofia Jönsson; Michael Hultström; Helle Prætorius Øhrwald; Uppsala universitet; []
    Nyckelord :Heart failure; Acute kidney injury; Angiotensin II; Fluid balance; Cardiac function; Renal function;

    Sammanfattning : Blood pressure and fluid regulation are kept constant through the interaction between heart and kidneys. When the systemic blood pressure decreases, the levels of the hormone Angiotensin II increase, leading to vasoconstriction and therefore increased blood pressure. LÄS MER

  5. 24. β-adrenergic stimulation of VEGF gene expression : intracellular signalling pathways

    Författare :Magnus J. Fredriksson; Georg Breier; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; zoofysiologi; Zoological physiology;

    Sammanfattning : In the present study, the intracellular signalling pathway mediating ß-adrenergic stimulation of the expression of the vascular endothelial growth factor (VEGF) gene was investigated.VEGF is an activator of angiogenesis, the formation of new blood vessels, and is considered to be a major regulator of both physiologically and pathologically related angiogenesis, as well as being essential for development of the vascular system. LÄS MER

  7. 25. Pharmacodynamic modeling of cardiovascular effects of Σb-antagonists and moxonidine : Special emphasis on tolerance and rebound effects

    Författare :Lena Brynne; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacy; FARMACI; PHARMACY; FARMACI; Biopharmaceutics; biofarmaci;

    Sammanfattning : Pharmacodynamic (PD) modeling was used to characterize and quantify the short- and long-term changes in cardiovascular effects following treatment with β-antagonists or imidazoline receptor agonist moxonidine, in spontaneous hypertensive rats and patients with congestive heart failure, respectively. The complex cardiovascular system is regulated by several feedback mechanisms with different time domains and gains. LÄS MER