Sökning: "Neurofilament"

Visar resultat 16 - 20 av 70 avhandlingar innehållade ordet Neurofilament.

1. 16. Neurological consequences of cardiac arrest

   Författare :Hans Rosén; Göteborgs universitet; []
   Nyckelord :cardiac arrest; prognosis; S-100; NSE; Neurofilament light protein; FIM; BNIS;

   Sammanfattning : An out-of-hospital cardiac arrest is a life-threatening event with very high early mortality. More than 50% of the patients who reach the emergency ward die, showing clinical signs of brain damage during the first weeks after admission. Survivors may suffer from post-ischemic encephalopathy, which influences their future lives. LÄS MER

3. 17. Prognostic subtypes in Parkinson’s disease and related disorders. Clinical, genetical, and biochemical markers for long-term social, motor, and cognitive development

   Författare :Emil Ygland Rödström; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; parkinson s disease; prognosis; Neurofilament light chain; clinical subtype; motor phenotype; MAPT R406W mutation; frontotemporal dementia; enthorinal cortex; progressive supranuclear palsy; tau isoform; brain-gut hypothesis; proteoglycan recognition protein; PGLYRP; RUNDC3B;

   Sammanfattning : .... LÄS MER

4. 18. White matter pathology in normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy. Clinical, CSF and MRI aspects

   Författare :Mats Tullberg; Göteborgs universitet; []
   Nyckelord :Normal pressure hydrocephalus; Subcortical arteriosclerotic encephalopathy; MRI; White matter changes; Cerebrospinal fluid; Sulfatide; Neurofilament protein;

   Sammanfattning : Normal pressure hydrocephalus (NPH) and subcortical arteriosclerotic encephalopathy (SAE) are common causes of gait disturbance, cognitive impairment and urinary incontinence in the elderly. In spite of a primarily different pathogenesis with a potentially reversible CSF dynamic disturbance in NPH and an irreversible microangiopathy in SAE, patients with NPH and SAE can present with similar symptoms and exhibit white matter changes that are difficult to distinguish, constituting a diagnostic and therapeutic challenge. LÄS MER

5. 19. Disorders of the cerebral white matter in children

   Författare :Ragnhildur Kristjánsdóttir; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leukoencephalopathy - children - neurological impairments - magnetic resonance imaging - ophthalmology - visual evoked potentials - cerebrospinal fluid - sulfatide - glial fibrillary acidic protein - gangliosides - neurofilament - tau protein - monoamine metabolites;

   Sammanfattning : The aims of this thesis were to describe the clinical spectrum in a large group of children characterised as having an abnormal magnetic resonance imaging (MRI) signal from cerebral white matter (WM) and to study the radiological, clinical and ophthalmological features in that subgroup where aetiology was unknown. We also wanted to look at biochemical markers in the cerebrospinal fluid (CSF) to elucidate pathological processes which were responsible for the WM abnormalities. LÄS MER

7. 20. Neurofilaments as biomarkers of neuronal damage

   Författare :Fani Pujol-Calderón; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurofilaments; biomarker; neurodegenerative disease; stroke;

   Sammanfattning : Different neurodegenerative diseases have overlapping symptomatology and pathology and have thus become a challenge to modern medicine to achieve a correct diagnosis. The aim of the thesis was to evaluate the use of neurofilaments as biomarkers of neuronal damage by testing their ability to discriminate between different neurodegenerative diseases as well as assessing whether higher neurofilments predict a poorer clinical outcome in ischemic stroke. LÄS MER