Sökning: "NATURVETENSKAP Kemi Biokemi"

Visar resultat 1 - 5 av 201 avhandlingar innehållade orden NATURVETENSKAP Kemi Biokemi.

  1. 1. 5-Aminolevulinic acid and derivatives thereof : properties, lipid permeability and enzymatic reactions

    Författare :Edvin Erdtman; Leif Eriksson; Tore Brinck; Örebro universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; 5-Aminolevulinic acid; tautomerization; PDT; DFT; MM; QM MM; Porphobilinogen synthase; Uroporphyrinogen III decarboxylase; membrane penetration; enzyme mechanism; Biophysical chemistry; Biofysikalisk kemi; Quantum chemistry; Kvantkemi; Theoretical chemistry; Teoretisk kemi; Fysikalisk kemi; Physical Chemistry; Biochemistry; Biokemi;

    Sammanfattning : 5-aminolevulinic acid (5-ALA) and derivatives thereof are widely usedprodrugs in treatment of pre-malignant skin diseases of the cancer treatmentmethod photodynamic therapy (PDT). The target molecule in 5-ALAPDTis protoporphyrin IX (PpIX), which is synthesized endogenously from5-ALA via the heme pathway in the cell. LÄS MER

  2. 2. Into the Membrane and Beyond : Improving Membrane Protein Over-Expression in Escherichia coli

    Författare :Mirjam Klepsch; Jan-Willem de Gier; Reinhard Grisshammer; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; Escherichia coli; membrane protein over-expression; proteomics; T7 RNA polymerase; peptide transport; strain engineering; Biochemistry; Biokemi; Biophysical chemistry; Biofysikalisk kemi; biokemi; Biochemistry;

    Sammanfattning : Membrane proteins fulfil a wide variety of essential functions in the cell and many are (potential) drug targets. Since their natural abundance is usually very low, most membrane proteins have to be over-expressed for functional and structural studies. LÄS MER

  3. 3. Development of a UV-B marker in plants

    Författare :Sanja Farkas; Åke Strid; Örebro universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; NATURAL SCIENCES; NATURVETENSKAP; Chemistry; Kemi; biokemi; Biochemistry;

    Sammanfattning : .... LÄS MER

  4. 4. Development of transgenic Arabidopsis thaliana and Daucus carota plant producing the p24 capsid protein from HIV-1 subtype C for the use as an edible plant-based vaccine model

    Författare :Ingrid Lindh; Åke Strid; Elin Grahn; Örebro universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; Molekylärbiologi; Biochemistry; Biokemi; NATURAL SCIENCES; NATURVETENSKAP; Chemistry; Kemi; biokemi; Biochemistry;

    Sammanfattning : .... LÄS MER

  5. 5. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry

    Författare :Kristina M. Orrling; Mats Larhed; Fredrik Almqvist; Uppsala universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; MEDICAL AND HEALTH SCIENCES; microwave-assisted chemistry; malaria; aspartic protease; plasmepsin; PfPM4; PmPM4; PoPM4; PvPM4; inhibitor; unsaturated lactone; unsaturated lactam; unsaturated amide; lactam; Bestmann s ylide; ionic liquid; polymerase chain reaction; thermophilic enzyme; Pharmaceutical chemistry; Läkemedelskemi; Organic synthesis; Organisk syntes; Biochemistry; Biokemi; Biochemistry; biokemi;

    Sammanfattning : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. LÄS MER