Sökning: "Methylenetetrahydrofolate reductase"

Visar resultat 6 - 10 av 15 avhandlingar innehållade orden Methylenetetrahydrofolate reductase.

1. 6. Folate, Hormones and Infertility : Different factors affecting IVF pregnancy outcome

   Författare :Tiina Murto; Anneli Stavreus-Evers; Agneta Skoog Svanberg; Sven-Eric Olsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; folic acid supplement; homocysteine; hormones; infertility; IVF; lifestyle factor; MTHFR; predictive value; socioeconomic factor; women; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Various hormones have been studied as regards prediction of pregnancy outcome after infertility treatment, but no ideal candidate has been found. Folate and genetic variations in folate metabolism have also been associated with infertility, but it remains unclear how these factors affect IVF pregnancy outcome. LÄS MER

3. 7. Cardiorespiratory fitness and cardiovascular disease risk factors in children and adolescents

   Författare :Jonatan Ruiz Ruiz; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Physical activity; fitness; fatness; insulin; homocysteine; metabolic risk score; accelerometry; gentyping; children; adolescents;

   Sammanfattning : Cardiovascular disease (CVD) events occur most frequently during or after the fifth decade of life, however, there is evidence indicating that the precursors of CVD has its origin already in the first or second decade of life. Low levels of physical activity and cardiorespiratory fitness are major modifiable determinants for the development of CVD in adults. LÄS MER

4. 8. Pathogenesis of Alzheimer's disease : focus on amyloid β-peptide, homocysteine and metals

   Författare :Dorota Religa; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Alzheimer's disease (AD) is a complex dementia disorder. It is characterized by the neuronal and synaptic loss, presence of neurofibrillary tangles and senile plaques, composed of amyloid β-peptide (Aβ) in the brain. LÄS MER

5. 9. Homocysteine and vascular morbidity and dementia in women. A prospective population study

   Författare :Dimitri Zylberstein; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Women; population study; dementia; Homocysteine; MTHFR; myocardial infarctions; lacunar infarcts; epidemiology;

   Sammanfattning : Homocysteine and cardiovascular morbidity and dementia in women - A prospective population study Dimitri Edin Zylberstein Institute of Medicine, The Sahlgrenska Academy, Department of Public Health and Community Medicine, Section of Primary Health Care, University of Gothenburg Abstract Purpose. The purpose of this thesis was to study cardiovascular morbidity and dementia in relation to homocysteine levels in women in a longitudinal, prospective population study over several decades. LÄS MER

7. 10. Exploring novel roles of metabolic enzymes MTHFD2 and PFKFB3 in cancer genome stability and their potential as anticancer therapeutic targets

   Författare :Nadilly Y Bonagas Villarreal; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Altered tumor metabolism has been described as early as the 1920s, but it was only in recent decades that proteomic and metabolomic studies revealed that the ways in which tumors rewire their nutrient and energy pathways are more diverse and have more implications for treatment outcome than previously thought. There is now a great interest in characterizing promising metabolic targets and identifying novel ways by which to exploit them for cancer treatment. LÄS MER