Sökning: "Medical and Health Sciences Basic Medicine Medical Genetics"
Visar resultat 36 - 40 av 371 avhandlingar innehållade orden Medical and Health Sciences Basic Medicine Medical Genetics.
36. Molecular Genetic and DNA Methylation Profiling of Chronic Lymphocytic Leukaemia : A Focus on Divergent Prognostic Subgroups and Subsets
Sammanfattning : Advancements in prognostication have improved the subdivision of chronic lymphocytic leukaemia (CLL) into diverse prognostic subgroups. In CLL, IGHV unmutated and IGHV3-21 genes are associated with a poor-prognosis, conversely, IGHV mutated genes with a favourable outcome. LÄS MER
37. Genetics, epigenetics and functional mechanisms in inherited corneal and retinal dystrophies
Sammanfattning : Inherited eye disorders (IED) are groups of genetically and clinically heterogenous conditions affecting different tissues in the eye. IED are most often progressive with reduced vision or legal blindness as outcome. LÄS MER
38. The role of estrogen and superoxide dismutase in cataractogenesis
Sammanfattning : .... LÄS MER
39. Functional organisation of the cell nucleus in the fission yeast, Schizosaccharomyces pombe
Sammanfattning : In eukaryotes the genome adopts a non-random spatial organisation, which is important for gene regulation. However, very little is known about the driving forces behind nuclear organisation. LÄS MER
40. Familial amyloidosis with polyneuropathy : studies of genetic factors modifying the phenotype of the disease
Sammanfattning : Background. Familial Amyloidosis with Polyneuropathy (FAP) is an autosomal dominantly inherited systemic amyloid disease. The disease is caused by mutations in the transthyretin (TTR) gene, where close to 100 different amyloidogenic mutations have been identified. LÄS MER