Sökning: "Magnaporthe grisea"

Hittade 4 avhandlingar innehållade orden Magnaporthe grisea.

  1. 1. Expression of Manganese Lipoxygenase and Site-Directed Mutagenesis of Catalytically Important Amino Acids : Studies on Fatty Acid Dioxygenases

    Författare :Mirela Cristea; Ernst H. Oliw; Chao Su; Olof Rådmark; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical pharmacology; Dioxygenase; Gaeumannomyces graminis; lipoxygenase; Magnaporthe grisea; oxylipin; Pichia pastoris; hydroperoxide isomerase; polyunsaturated fatty acids; Farmaceutisk farmakologi; Pharmaceutical pharmacology; Farmaceutisk farmakologi;

    Sammanfattning : Polyunsaturated fatty acids can be bioactivated by two families of dioxygenases, which either contain non-heme iron (lipoxygenases) or heme (cyclooxygenases, linoleate diol synthases and α-dioxygenases).Lipoxygenases and their products play important roles in the pathophysiology of plants and fungi. LÄS MER

  2. 2. Synthesis of Bioactive Analogues of Marasmane Dialdehydes

    Författare :Daniel Röme; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Cancer; Enantioselective synthesis; Totalsynthesis; Semisynthesis; Cytotoxicity; Anti-tumor activity; Isovelleraloids; Marasmic acid; Marasmane dialdehydes; Isovelleral;

    Sammanfattning : The modification of drugs into pro-drugs is an attractive concept allowing you to tweak the chemical and physical properties of a drug without changing the original structure of the active compound. In principle, any compound possessing a preferred biological activity can be transformed into a pro-drug. LÄS MER

  3. 3. Novel biologically active compounds by semisynthesis with fungal metabolites

    Författare :Johan Eriksson Bajtner; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; bioactive compounds.; isovelleral; podoscyphic acid; Natural products; semisynthesis;

    Sammanfattning : Natural products have been shown to be an important source of novel compounds for the development of new drugs and pesticides. However, many biologically active natural products contain reactive functionalities that make them toxic. LÄS MER

  4. 4. Structural studies of saccharopine reductase and purple acid phosphatase

    Författare :Eva Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lysine is synthesised in two different ways in living organisms, either by the diaminopimelate pathway or the [alpha]-aminoadipate pathway. These routes belong to the aspartate and the glutamate family of amino acid biosynthesis, respectively. LÄS MER