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Visar resultat 21 - 25 av 51 avhandlingar som matchar ovanstående sökkriterier.

1. 21. Multivariate non-invasive measurements of skin disorders

   Författare :Josefina Nyström; Britta Lindholm-Sethson; Paul SLU Geladi; Lars Noergaard; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Multivariate Data Analysis; Non-invasive techniques; Clinical studies; Principal Component Analysis; Partial Least Squares Discriminant Analysis; Wilcoxon Signed Rank Sum Test; Near-InfraRed spectroscopy; Frequency Bio Impedance Analysis of whole body; Laser Doppler Imaging; Digital Colour Photography; Analytical chemistry; Analytisk kemi;

   Sammanfattning : The present thesis proposes new methods for obtaining objective and accurate diagnoses in modern healthcare. Non-invasive techniques have been used to examine or diagnose three different medical conditions, namely neuropathy among diabetics, radiotherapy induced erythema (skin redness) among breast cancer patients and diagnoses of cutaneous malignant melanoma. LÄS MER

3. 22. Fluid Dynamics and Granular Growth in High Shear Wet Granulation

   Författare :Anders Darelius; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coalescence kernel; Frictional Stress Models; Laser Doppler Anemometry; Population balances; CFD; EFD; High shear granulation; High speed imaging; Multi-dimensional; Multiphase flows;

   Sammanfattning : High shear wet granulation is a key step in the manufacturing of tablets in the pharmaceutical industry. From the pharmaceutical industry’s point of view, there is a desire for predictive quantitative process models to be able to make in-silico process and scale-up simulations, which would shorten and reduce the cost of technology transfer from laboratory scale to manufacturing scale in drug development. LÄS MER

4. 23. Clinical and experimental studies on oxidized fragrance terpenes as contact allergens

   Författare :Johanna Bråred Christensson; Göteborgs universitet; []
   Nyckelord :autoxidation; contact allergy; limonene; linalool; colophonium; limonene-1-hydroperoxide; limonene-2-hydroperoxide; 15-hydroperoxyabietic acid; 15-HPA; terpenes; local lymph node assay; LLNA; Freunds complete adjuvant test; FCAT; patch testing; laser Doppler imaging; skin irritation; visual reading;

   Sammanfattning : The work presented in this thesis aims to improve the possibilities for diagnosing contact allergy to oxidized limonene and linalool and to, in patients, study contact allergy from structurally closely related hydroperoxides with regard to their specificity, potency and cross-reactivity. The fragrance terpenes limonene (from citrus oil) and linalool (from lavender oil) are widely used in household and industrial products. LÄS MER

5. 24. Between the Probe and the Pump : An experimental study on cardiac performance analysis based on Echocardiography, tissue and laser Doppler

   Författare :Laila Hübbert; Birgitta Janerot-Sjöberg; Ulf Dahlström; Sven-Erik Ricksten; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Echocardiography is an ultrasound-based bedside, non-invasive and easily available cardiac diagnostic technique visualising the heart’s morphology and function. Quantification of cardiac wall motion can be measured with the tissue Doppler Imaging (TDI) modality which provides in humans a high diagnostic capacity to differentiate healthy from diseased myocardium with reduced function. LÄS MER

7. 25. Photodynamic therapy and laser-based diagnostic studies of malignant tumours

   Författare :Ingrid Wang; Medicinskt lasercentrum; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protoporphyrin IX PpIX ; delta -aminolevulinic acid ALA ; photosensitizer; basal cell carcinoma BCC ; Photodynamic therapy PDT ; laser-induced fluorescence LIF ; Cytology; oncology; cancerology; Cytologi; onkologi; cancer;

   Sammanfattning : Two non-thermal regimens of light interaction with biological tissue, that are in a natural way connected, are discussed in the present thesis. These are photodynamic therapy (PDT) for the treatment of malignant tumours and laser-induced fluorescence (LIF) for tissue characterization. LÄS MER