Sökning: "Photodynamic therapy PDT"

Visar resultat 1 - 5 av 27 avhandlingar innehållade orden Photodynamic therapy PDT.

  1. 1. Methods, Instrumentation and Mechanisms for Optical Characterization of Tissue and Treatment of Malignant Tumours

    Författare :Sara Pålsson; Atomfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; temperature; perfusion; PDT; photodynamic therapy; mechanisms; tissue characterization; instrumentation; optical biopsy; fluorescence spectroscopy; spectroscopy techniques; Raman spectroscopy; interstitial photodynamic therapy; photodynamic threshold dose; Atomic and molecular physics; Atom- och molekylärfysik;

    Sammanfattning : In this thesis, different optical methods utilising visible light for characterization of tissue have been developed and evaluated. The feasibility of many of these methods has been demonstrated in the laboratory or in animal experiments. LÄS MER

  3. 2. Spectroscopic techniques for photodynamic therapy dosimetry

    Författare :Ann Johansson; Atomfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Atomic and molecular physics; diffuse light spectroscopy; photodynamic therapy; biomedical optics; Atom- och molekylärfysik;

    Sammanfattning : Photodynamic therapy (PDT) as a cancer treatment modality relies on the simultaneous presence of three components; light, photosensitiser and oxygen. Once excited by the light, the photosensitiser can interact with oxygen, leading to the formation of toxic oxygen species. LÄS MER

  4. 3. Exploring nanosystems for biomedical applications focusing on photodynamic therapy and drug delivery

    Författare :Vladimir Kirejev; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Photodynamic therapy; PDT enhancement; Nitric oxide; NO-based PDT; Targeted drug delivery; Galectin-3; mTHPP; Cyclodextrin; CD-mTHPP conjugate; PpIX AuNP combination; Two-photon microscopy; FLIM; Cell phototoxicity; Ex vivo skin;

    Sammanfattning : The increasing incidences of cancer and related deaths call for the development of new and improved treatment modalities. Photodynamic therapy (PDT) today is an alternative to conventional treatments, but has limitations. This thesis explores different nanosystems with aim to improve PDT focusing on spectroscopic and ex vivo studies. LÄS MER

  5. 4. Photodynamic therapy- pain and aspects of pain relief

    Författare :Christina Halldin; Göteborgs universitet; []
    Nyckelord :actinic keratosis; field cancerization; interviews; nerve block; pain; photodynamic therapy; transcutaneous electrical nerve stimulation;

    Sammanfattning : Photodynamic therapy – pain and aspects of pain relief Christina Halldin Department of Dermatology and Venereology, Sahlgrenska University Hospital, Institute of Clinical Sciences at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden ABSTRACT Photodynamic therapy (PDT) is a non-invasive treatment option for superficial basal cell carcinoma (BCC), squamous cell carcinoma (SCC) in situ or Bowen’s disease (BD), and actinic keratoses (AK). One of the advantages of PDT is the possibility to treat field cancerization. LÄS MER

  7. 5. Laser diode systems for photodynamic therapy and medical diagnostics

    Författare :Eva Samsöe Andersen; Atomfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; quasi-phasematching; photodynamic therapy; laser-induced fluorescence; medical laser systems.; Histology; cytochemistry; histochemistry; tissue culture; Histologi; Laserteknik; Laser technology; cytokemi; histokemi; vävnadskultur; Diagnostik; Diagnostics; second harmonic generation; pulsed lasers; spatial filtering; Diode lasers; optical feedback; Fysicumarkivet A:2004:Samsöe Andersen;

    Sammanfattning : This work concerns techniques for improvement of the coherence properties of diode lasers so that they may be used in two specific medical applications: (Interstitial) photodynamic therapy (PDT) and laser-induced fluorescence diagnostics. In the first application, spatial coherence is crucial, since the treatment light should be delivered through relatively thin optical fibers to optimize treatment and to facilitate minimally invasive treatment. LÄS MER