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Visar resultat 1 - 5 av 72 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Soluble amyloid-β aggregates in Alzheimer’s disease

    Författare :Hillevi Englund; Frida Ekholm Pettersson; Lars NG Nilsson; Lars Lannfelt; Dominic M Walsh; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Geriatrics and medical gerontology; Geriatrik och medicinsk gerontologi; Geriatrics; geriatrik;

    Sammanfattning : Soluble oligomeric aggregates of the amyloid-β (Aβ) peptide are suggested to initiate Alzheimer's disease (AD), leading to impaired synapse signalling, widespread neuronal death and loss of cognitive functions. These aggregates seem tightly linked to disease progression, and have therefore gained much attention as potential novel disease markers. LÄS MER

  3. 2. Targeting Early Stages of Alzheimer’s Disease in a Transgenic Model

    Författare :Anna Lord; Lars Nilsson; Lars Lannfelt; Frida Ekholm Pettersson; Thomas Bayer; Uppsala universitet; []
    Nyckelord :Geriatrics; geriatrik;

    Sammanfattning : The Arctic mutation causes early-onset Alzheimer’s disease (AD), and makes amyloid-β (Aβ) peptides more prone to form Aβ protofibrils. The aims of this thesis were to investigate the mechanisms of the Arctic mutation in vivo, and to use transgenic models to determine the role of early intermediates of Aβ aggregation, like protofibrils, in the pathogenesis. LÄS MER

  4. 3. Efficient Methods to Calculate Mutual Coupling between Generic Antennas on Large Platforms

    Författare :Johan Malmström; B. Lars G. Jonsson; Lars Pettersson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : This thesis presents research on methods for calculating the mutual coupling between antennas. The mutual coupling between antennas is a measure of the amount of energy transmitted from one antenna that is received by another, and is a key parameter when installing antennas on platforms, such as aircraft. LÄS MER

  5. 4. Electromagnetic Simulation, Analysis and Design with Application to Antennas and Radar Absorbers

    Författare :Alireza Motevasselian; Lars Jonsson; Lars Pettersson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : The present thesis considers two different subjects in the research area of electromagnetics. The first part is concerned with antenna design and the second with radar absorbers and rasorber.In the first part, a novel excitation technique for cylindrical dielectric resonator antennas is introduced to produce circular polarization. LÄS MER

  7. 5. Colloidal interactions and arrested dynamics of cellulose nanofibrils

    Författare :Malin Nordenström; Lars Wågberg; Torbjörn Pettersson; Lars Göran Ödberg; Andreas Fall; Wim Thielemans; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cellulose nanofibrils; colloidal interactions; colloidal stability; arrested state; colloidal glass; colloidal gel; tracer diffusion; counterion; steric stabilization; redispersion; redispersion agent; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : Over the past decades, concerns for the environment have increased and efforts to achieve a sustainable society have intensified. One particular challenge is to replace fossil-based plastics with biodegradable materials produced from renewable resources. LÄS MER