Sökning: "Knockout processes"

Visar resultat 1 - 5 av 76 avhandlingar innehållade orden Knockout processes.

  1. 1. Cosmic Molecules and Clusters : Knockout Driven Reactions

    Författare :Naemi Florin; Henning Zettergren; Michael Gatchell; Cyril Falvo; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Clusters; Fullerenes; PAHs; Knockout; Physics; fysik;

    Sammanfattning : Fullerenes and PAHs (polycyclic aromatic hydrocarbons) are two families of carbon based molecules. These are both present in the interstellar medium, and are there believed to play important roles in various processes, including the formation of stars in the case of PAHs. LÄS MER

  3. 2. The role of knockout driven fragmentation in collision with isolated complex molecular systems

    Författare :Linda Giacomozzi; Henning Zettergren; Henrik Öström; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Knockout processes; PAHs; HPAHs; porphyrins; fysik; Physics;

    Sammanfattning : This licentiate thesis covers results from collision induced dissociation (CID) experiments of Polycyclic Aromatic Hydrocarbons (PAHs), hydrogentated PAHs (HPAHs) and porphyrins. PAHs and HPAHs are believed to play key roles in the evolution of complex molecules in space, while porphyrins are essential for various functions in living organisms. LÄS MER

  4. 3. The Biological Importance of the Amino Acid Transporter SLC38A10 : Characterization of a Knockout Mouse

    Författare :Frida A. Lindberg; Robert Fredriksson; Erika Roman; Karin Nordenankar; Vootele Vöikar; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solute carrier; SLC; SNAT10; SLC38A10; phenotyping; behavior; amino acids; knockout mouse model; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : The biggest group of transporters, the solute carriers (SLCs), has more than 400 members, and about 30% of these are still orphan. In order to decipher their biological function and possible role in disease, there is a need for characterization of these. LÄS MER

  5. 4. The role of TGF-§ in hematopoiesis

    Författare :Jonas Larsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Transforming growth factor-§; Cre loxP system; receptor; knockout; embryogenesis; angiogenesis; hematopoiesis; hematopoietic stem cell; inflammation; Medicine human and vertebrates ; Medicin människa och djur ;

    Sammanfattning : Transforming growth factor-§ (TGF-§) is a potent, multifunctional growth factor affecting virtually all cell types, regulating critical physiological processes like immune response, wound healing, angiogenesis, and tumor development. A large number of studies in vitro have also implicated a critical role of TGF-§ in regulating hematopoiesis by inhibiting proliferation of hematopoietic stem cells (HSCs). LÄS MER

  7. 5. Functions of platelet-derived growth factor-A during organogenesis

    Författare :Linda Karlsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; platelet-derived growth factor-A; knockout; mouse organogenesis; epithelial-mesenchymalinteractions; skin; hair follicles; CNS; lung; gastrointestinal villus;

    Sammanfattning : The formation of organs during embryonic development is calledorganogenesis. This process is regulated by the genes residing in the genome. LÄS MER