Sökning: "Kiran Busayavalasa"

Hittade 1 avhandling innehållade orden Kiran Busayavalasa.

1. 1. Regulators of Membrane Fluidity

   Författare :Kiran Busayavalasa; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRIG; membrane fluidity;

   Sammanfattning : Caenorhabditis elegans PAQR-2 (a homolog of the mammalian AdipoR1 and AdipoR2 proteins) and IGLR-2 (homolog of the mammalian LRIG proteins) form a complex at the plasma membrane that regulates fatty acid desaturation to protect against saturated fatty acid-induced membrane rigidification. Maintenance of membrane homeostasis is fundamental for most cellular processes and, given its importance, robust regulatory mechanisms must exist that adjust lipid composition to compensate for dietary variation. LÄS MER