Sökning: "Jacqueline"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet Jacqueline.

1. 1. FGF signaling in specification of hESC-derived definitive endoderm

   Författare :Jacqueline Ameri; Stamcellscentrum (SCC); []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Diabetes affects around 200 million people worldwide. Curing diabetes would require the prevention of autoimmune destruction of beta cells and restoration of the beta cell mass restored either through regeneration or transplantation of the insulin producing cells. LÄS MER

3. 2. Molecular imaging of the serotonin system in human behaviour

   Författare :Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

   Sammanfattning : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. LÄS MER

4. 3. Mechanism of conditional regulation of the bHLH/PAS dioxin receptor

   Författare :Jacqueline McGuire; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The intracellular dioxin receptor is a bHLH/PAS protein which mediates signal transduction by dioxin and upon heterodimerisation with the bHLH/PAS partner factor Arnt, functions as a ligand-activated transcription factor by binding to specific xenobiotic response elements in promoters of target genes. Although the physiological function of the dioxin receptor and the nature of a possible physiological ligand are presently not known, targeted disruption of the mouse dioxin receptor gene has indicated that the receptor may play an important role in hepatic development. LÄS MER

5. 4. Gene dose imbalances in children with mental retardation

   Författare :Jacqueline Schoumans; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mental retardation; MCA MR syndromes; cromosome abnormalities; subtelomeric FISH; comparative genomichybridization; array-CGH;

   Sammanfattning : Submicroscopic chromosome aberrations can cause mental retardation (MR), congenital malformations and miscarriage. It is difficult to estimate the contribution of cytogenetic abnormalities to MR because of relatively low detection sensitivity of conventional cytogenetic methods used in the diagnostic setting. LÄS MER

7. 5. The allure of the exotic : The social use of non-local raw materials during the Stone Age in Sweden

   Författare :Jacqueline Taffinder; Uppsala universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; Archaeology; Arkeologi; Archaeology subjects; Arkeologiämnen; arkeologi; Archaeology;

   Sammanfattning : By use of ethnoarchaeological method this thesis attempts to investigate the social roles of non-local raw materials. Personal ornaments are studied in a world-wide range of ethnographic contexts, attention being focused on the origin of raw materials used to make these objects and the social use they assume in the 64 different societies analysed. LÄS MER