Sökning: "MADAM"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet MADAM.

  1. 1. PET studies of the serotonin transporter in the human brain

    Författare :Johan Lundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :positron emission tomography; MADAM; WAY 100635; 5-HTT; 5-HT1A receptors; receptor occupancy; major depressive disorder; citalopram; escitalopram;

    Sammanfattning : The serotonin (5-HT) system attracts considerable attention in research on the pathophysiology and drug treatment of neuropsychiatric disorders. The brain imaging technique Positron Emission Tomography (PET) allows for examination of neurotransmission systems in the human brain in vivo. LÄS MER

  3. 2. Molecular imaging of the serotonin system in human behaviour

    Författare :Jacqueline Borg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :positron emission tomography; serotonin; 5-HT1A receptor; 5-HTT; 5HTTÖPR; WAY100635; MADAM; cognitive functions; personality;

    Sammanfattning : The serotonin (5-HT) neurotransmission system has a role in essential physiological and psychological functions such as sleep, eating behaviour, sexuality, perception, emotion and cognition. Individual measures of serotonin biomarkers in the living human brain can be obtained using positron emission tomography (PET) imaging, direct measures of. LÄS MER

  4. 3. PET evaluation of central serotonergic neurotransmission in women

    Författare :Hristina Jovanovic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :PET; serotonin; 5-HT1A receptor; 5-HTT; WAY100635; MADAM; premenstrual dysphoric disorder; borderline personality disorder; gonadal hormones;

    Sammanfattning : The serotonin (5-HT) system is of central interest in the patophysiology and treatment of several psychiatric disorders including depression, anxiety and suicide. In women, functioning of the 5-HT system is of particular importance since they have been found to suffer more often from 5-HT-associated disorders compared to men. LÄS MER

  5. 4. High-performance Nickel-based Superalloys for Additive Manufacturing

    Författare :Jinghao Xu; Johan Moverare; Ru Peng; Chinnapat Panwisawas; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Nickel-based superalloy; Alloy design; Laser powder bed fusion; Cracking susceptibility; Additive manufacturability; Heat treatment; γ′ precipitate; High-temperature mechanical property; Creep; Oxidation;

    Sammanfattning : Additive manufacturing (AM), e.g., laser powder bed fusion (LPBF) technique, has become a powerful manufacturing process for producing metallic components with the advantages of design freedom, net-shape-forming flexibility, product customization, and reduced lead time to market. LÄS MER

  7. 5. The longitudinal biology of depression : PET studies of the dopamine and serotonin systems

    Författare :Jonas Svensson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The involvement of monoamine neurotransmission in the pathophysiology of depression was established already in the 1960s. However despite an abundance of research, the exact role of the serotonin (5-HT) and dopamine systems in depression have remained elusive. LÄS MER