Avancerad sökning

Visar resultat 16 - 20 av 131 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. The role of natural killer cells and inflammatory mediators in preeclamptic pregnancies

    Författare :Nora Bachmayer; Eva Sverremark-Ekström; Katarina Bremme; Lucia Mincheva-Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; preeclampsia; NK cells; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The maternal immune system must be able to adjust during pregnancy and accept the foetus that expresses paternal antigens. These changes are found both in placenta and circulation, including a mild inflammatory response. NK cells are abundant during the early part of pregnancy in placenta and are thought to be important for placental development. LÄS MER

  3. 17. Innate and acquired immunity to commensal bacteria

    Författare :Christina Hessle; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The innate immune system recognises molecular patterns shared by large groups of micro-organisms. Monocytes and macrophages respond to microbes by production of substances which act in concert to promote effective clearance of bacteria. LÄS MER

  4. 18. Studies on cytokine mRNA expression in mononuclear cells in neuroimmunological diseases

    Författare :Darius Matusevicius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS), characterized by perivascular accumulation of blood mononuclear cells (MNC) and patchy demyelination. High levels of circulating myelin antigen specific T and B cells, with an accumulation in cerebrospinal fluid (CSF), suggest the involvement of cytokines in the pathogenesis of MS. LÄS MER

  5. 19. Immunological effects of interferon-beta and glatiramer acetate in multiple sclerosis

    Författare :Yassir Hussien; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Multiple sclerosis; Interferon-beta; Glatiramer acetate; Dendritic cells; Mononucealar cells;

    Sammanfattning : Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system, which results in demyelination, axonal loss and neurological deficits. The aetiology is unknown, however, immunopathological events, which are believed to be of an autoimmune nature, are considered to be responsible for the development of the disease. LÄS MER

  7. 20. Preterm and term cervical ripening : studies on CRH, HMGB1, toll-like receptors, cytokines and matrix metalloproteinases

    Författare :Aurelija Dubicke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cervical fibroblasts; cervical ripening; cervix; chemokines; cytokines; CRH; HMGB1; interleukin; labor; preterm; preterm labor; matrix metalloproteinases; pregnancy; PPROM; Tolllike receptors;

    Sammanfattning : Objective: Preterm birth (PTB) is the leading cause of neonatal mortality and morbidity. Despite the existing treatment, the frequency of PTB has not changed in the past thirty years. Incomplete understanding of the biological and pathophysiological mechanisms underlying preterm delivery is the major obstacle to preventing PTB. LÄS MER